Dipterocarpol | CAS:471-69-2 | Manufacturer ChemFaces

Dipterocarpol

ChemFaces products have been cited in many studies from excellent and top scientific journals

Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC

How to Order

Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com

Delivery time

Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal

Citing Use of our Products

More Impact Factor than five Cite...

* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.

According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.

Size /Price /Stock	10 mM * 1 mL in DMSO / Inquiry
Other Packaging	*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap

Featured Products

More...

Ginkgolic acid C13:0

Catalog No: CFN98507
CAS No: 20261-38-5
Price: $168/20mg

Doxycycline

Catalog No: CFN90251
CAS No: 564-25-0
Price: $ /

Kaempferol 3-O-beta-sophoroside

Catalog No: CFN92372
CAS No: 19895-95-5
Price: $268/20mg

4-Methoxyglucobrassicin

Catalog No: CFN00505
CAS No: 83327-21-3
Price: $ / mg

Protopine

Catalog No: CFN99399
CAS No: 130-86-9
Price: $50/20mg

Gypenoside XIII

Catalog No: CFN95239
CAS No: 80325-22-0
Price: $288/10mg

Spathulenol

Catalog No: CFN97150
CAS No: 6750-60-3
Price: $ /

Alisol A 24-acetate

Catalog No: CFN90198
CAS No: 18674-16-3
Price: $118/20mg

Aerugidiol

Catalog No: CFN92621
CAS No: 116425-35-5
Price: $318/5mg

Pinocembrin 7-O-(3''-galloyl-4'',6...

Catalog No: CFN90881
CAS No: 205370-59-8
Price: $318/20mg

Description:

Dipterocarpol is a dammarane-type triterpenoid, as are the major bioactive compounds of ginseng. Dipterocarpol A shows moderate acetylcholinesterase inhibitory activity with the IC50 value of 8.28 uM.

Targets:

P450 (e.g. CYP17) | AChE

In vitro:

FEBS J. 2012 May;279(9):1663-74.

Hydroxylation of the triterpenoid dipterocarpol with CYP106A2 from Bacillus megaterium.[Pubmed: 22269065]

Namely Dipterocarpol and betulin. Dipterocarpol is the most promising compound for biotechnological application because it is a dammarane-type triterpenoid, as are the major bioactive compounds of ginseng.
METHODS AND RESULTS:
The Dipterocarpol hydroxylation products were analysed by NMR and identified as 7β-hydroxyDipterocarpol and 7β,11α-dihydroxyDipterocarpol. To investigate the putative bioactive properties of these novel compounds, in vitro cytotoxicity assays with HeLa and COS-1 cells were performed. The substrate Dipterocarpol and the dihydroxylated product did not show cytotoxic activity in our study. By contrast, the 7β-hydroxylated product was found to be cytotoxic to both tested cell lines.
CONCLUSIONS:
This study highlights the potency of CYP106A2 as a versatile biocatalyst for the bioconversion of natural products into pharmaceutically relevant bioactive products.

Dipterocarpol Description

Source:	The herbs of Aglaia odorata
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Structure Identification:

Planta Med. 2014 Nov;80(17):1641-6.

Oligostilbenoids with acetylcholinesterase inhibitory activity from Dipterocarpus alatus.[Pubmed: 25317771]

METHODS AND RESULTS:
Phytochemical investigation of the stem wood of Dipterocarpus alatus led to the isolation and characterization of four new oligostilbenoids, Dipterocarpols A-D (1-4), together with two known resveratrol oligomers, hopeahainol (5) and hopeafuran (6). The structures of the new compounds were determined by comprehensive spectral analysis including 1D and 2D NMR, and high-resolution MS. The absolute configurations were determined by NOESY and CD spectra.
CONCLUSIONS:
Dipterocarpol A (1) and hopeahainol A (5) showed moderate acetylcholinesterase inhibitory activity with IC50 values of 8.28 μM and 11.28 μM, respectively. Furthermore, the discovery of compound 3 gave the first evidence that the biosynthetic origin of resveratrol aneuploids is related to the loss of a half resveratrol unit by oxidative cleavage.

Product Name	Dipterocarpol
Price:
CAS No.:	471-69-2
Catalog No.:	CFN98705
Molecular Formula:	C₃₀H₅₀O₂
Molecular Weight:	442.7 g/mol
Purity:	>=98%
Type of Compound:	Triterpenoids
Physical Desc.:	Powder
Source:	The herbs of Aglaia odorata
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Anticholinesterase Compound Library Triterpenoids Compound Library P450 (e.g. CYP17) Inhibitor Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.2589 mL	11.2943 mL	22.5887 mL	45.1773 mL	56.4717 mL
5 mM	0.4518 mL	2.2589 mL	4.5177 mL	9.0355 mL	11.2943 mL
10 mM	0.2259 mL	1.1294 mL	2.2589 mL	4.5177 mL	5.6472 mL
50 mM	0.0452 mL	0.2259 mL	0.4518 mL	0.9035 mL	1.1294 mL
100 mM	0.0226 mL	0.1129 mL	0.2259 mL	0.4518 mL	0.5647 mL

CFN90349	25(R)-Hydroxyprotopanaxadiol	83349-37-5	478.75	C₃₀H₅₄O₄
CFN90351	25(S)-Hydroxyprotopanaxatriol	113539-03-0	494.75	C₃₀H₅₄O₅
CFN99717	Gypenoside XLIX	94987-08-3	1047.23	C₅₂H₈₆O₂₁
CFN96019	Palbinone	139954-00-0	358.5	C₂₂H₃₀O₄
CFN96254	Dammarenediol II 3-O-caffeate	171438-55-4	606.9	C₃₉H₅₈O₅
CFN98705	Dipterocarpol	471-69-2	442.7	C₃₀H₅₀O₂
CFN97232	20,24-Dihydroxydammar-25-en-3-one	75069-59-9	458.7	C₃₀H₅₀O₃
CFN97092	24,25-Epoxydammar-20(21)-en-3-one	63543-52-2	440.7	C₃₀H₄₈O₂
CFN98922	Dammar-20(21)-en-3,24,25-triol	55050-69-6	460.7	C₃₀H₅₂O₃
CFN97093	24,25-Dihydroxydammar-20-en-3-one	63543-53-3	458.7	C₃₀H₅₀O₃