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Echinatine N-oxide
Echinatine N-oxide
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Echinatine N-oxide
Price:
CAS No.: 20267-93-0
Catalog No.: CFN00256
Molecular Formula: C15H25NO6
Molecular Weight: 315.36 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The herbs of Eupatorium cannabinum L.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Reference standards.
Echinatine N-oxide Description
Source: The herbs of Eupatorium cannabinum L.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
More...

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.171 mL 15.8549 mL 31.7098 mL 63.4196 mL 79.2745 mL
5 mM 0.6342 mL 3.171 mL 6.342 mL 12.6839 mL 15.8549 mL
10 mM 0.3171 mL 1.5855 mL 3.171 mL 6.342 mL 7.9274 mL
50 mM 0.0634 mL 0.3171 mL 0.6342 mL 1.2684 mL 1.5855 mL
100 mM 0.0317 mL 0.1585 mL 0.3171 mL 0.6342 mL 0.7927 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Fitoterapia, 1990.
Pyrrolizidine alkaloids from Lindelofia longiflora.[Reference: WebLink]

METHODS AND RESULTS:
Although many pyrrolizidine alkaloids are hepatotoxic and can cause deaths in grazing livestock, N-oxides of heliotridine esters have been shown to possess anti-tumour activity. Newly described constituents of L. longiflora fresh plant material are echinatine (0.3%), and Echinatine N-oxide (0.6%).
CFN00256Echinatine N-oxide20267-93-0315.36C15H25NO6
CFN00257Cynoglossamine120193-39-7445.51C24H31NO7
CFN00258Rinderine6029-84-1299.37C15H25NO5
CFN00470Rinderine N-oxide137821-16-0315.4C15H25NO6
CFN00259Echiumine633-16-9381.47C20H31NO6
CFN00260Myoscorpine82535-76-0381.47C20H31NO6
CFN00261Symlandine74410-74-5381.47C20H31NO6
CFN00251Curassavine68385-70-6299.41C16H29NO4
CFN00254Echimidine520-68-3397.47C20H31NO7
CFN00452Echimidine N-oxide41093-89-4413.5C20H31NO8
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