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Effusol
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Effusol
Price: $238 / 10mg
CAS No.: 73166-28-6
Catalog No.: CFN90815
Molecular Formula: C17H16O2
Molecular Weight: 252.3 g/mol
Purity: >=98%
Type of Compound: Phenols
Physical Desc.: Powder
Source: The stem of Juncus effusus L.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $99.2 / In-stock
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Effusol can induce caspase-3-mediated cytotoxicity in HT22 cells.
Targets: Caspase
In vitro:
J Nat Med. 2015 Jul;69(3):421-6.
Chemical constituents isolated from Juncus effusus induce cytotoxicity in HT22 cells.[Pubmed: 25794817 ]
Effususol A (1), a new 9,10-dihydrophenanthrene, has been isolated from the medullae of Juncus effusus along with ten known compounds, Effusol (2), dehydroEffusol (3), juncusol (4), dehydrojuncusol (5), juncuenin B (6), dehydrojuncuenin B (7), juncuenin D (8), luteolin (9), luteolin 5-methyl ether (10), and 4-hydroxy-2,3-dimethyl-2-nonen-4-olide (11).
METHODS AND RESULTS:
The structure of 1 was elucidated on the basis of spectroscopic data. 2, 4, 6, 7, and 8 have induced caspase-3-mediated cytotoxicity in HT22 cells.
In vivo:
Nat Prod Commun. 2014 Aug;9(8):1177-8.
Two new anxiolytic phenanthrenes found in the medullae of Juncus effusus.[Pubmed: 25233602]
Six phenanthrenes, 2-methoxy-7-hydroxy-1-methyl-5-vinyl phenanthrene (1), juncusin (2), dehydroEffusol (3), juncusol (4), Effusol (5), and dehydroeffusal (6), were isolated from the medullae of Juncus effusus L.
METHODS AND RESULTS:
Compounds 1 and 2 were identified as being new structures, and both of them showed anxiolytic activity at dosages of 10 and 2.5 mg/kg, respectively.
Effusol Description
Source: The stem of Juncus effusus L.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
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IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

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IF=13.903(2019)

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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.9635 mL 19.8177 mL 39.6354 mL 79.2707 mL 99.0884 mL
5 mM 0.7927 mL 3.9635 mL 7.9271 mL 15.8541 mL 19.8177 mL
10 mM 0.3964 mL 1.9818 mL 3.9635 mL 7.9271 mL 9.9088 mL
50 mM 0.0793 mL 0.3964 mL 0.7927 mL 1.5854 mL 1.9818 mL
100 mM 0.0396 mL 0.1982 mL 0.3964 mL 0.7927 mL 0.9909 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
trans-Caryophyllene

Catalog No: CFN90502
CAS No: 87-44-5
Price: $30/20mg
Salidroside

Catalog No: CFN99177
CAS No: 10338-51-9
Price: $40/20mg
Kaempferol-3-O-galactoside

Catalog No: CFN92079
CAS No: 23627-87-4
Price: $238/10mg
Nodakenin

Catalog No: CFN90232
CAS No: 495-31-8
Price: $70/20mg
Astragaloside II

Catalog No: CFN99173
CAS No: 84676-89-1
Price: $50/20mg
Pinobanksin

Catalog No: CFN98917
CAS No: 548-82-3
Price: $338/5mg
Acacetin

Catalog No: CFN98744
CAS No: 480-44-4
Price: $30/20mg
Citric acid

Catalog No: CFN98551
CAS No: 77-92-9
Price: $30/20mg
Sagittatoside B

Catalog No: CFN90211
CAS No: 118525-36-3
Price: $298/10mg
Praeruptorin B

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