ChemFaces is a professional high-purity natural products manufacturer.
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1. Reference standards
2. Pharmacological research
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More articles cited ChemFaces products.
Phytomedicine.2018 Jan 1;Phytomedicine. 2017 Jan 15;Nat Plants. 2016 Dec 22Ajchem JournalJAN. 2014J Ethnopharmacol. 2017 Feb 2;
Evid Based Complement Alternat Med. 2017:1583185Jour. of Stored Pro & Postharvest Res.March 2016Food Science and Bio.31 October 2016Lab On a Chip21 Feb 2018;Int J Mol Sci.2017 Nov 30;
Biomed Chromatogr. 2016 Mar 23.Molecules. 2017 Dec 4;J Pharm Biomed Anal.2018 Mar 20;Cytotechnology. 2017 Apr 3.
Our products had been exported to the following research institutions and universities, And still growing.
Kyung Hee University (Korea)University Medical Center Mainz (Germany)Colorado State University (USA)University of Hertfordshire (United Kingdom)
Shanghai Institute of Organic Ch... (China)University of Illinois (USA)Srinakharinwirot University (Thailand)Julius Kühn-Institut (Germany)
Utah State University (USA)Rio de Janeiro State University (Brazil)Nanjing University of Chinese Me... (China)
|| Epigomisin O is a natural product from Schizandra chinensis.|
|J Nat Prod. 2006 Dec;69(12):1697-701. |
|Rubrisandrins A and B, lignans and related anti-HIV compounds from Schisandra rubriflora.[Pubmed: 17190445 ]|
METHODS AND RESULTS:
Bioactivity-directed fractionation of an ethanolic extract of the fruits of Schisandra rubriflora led to the isolation and identification of dibenzocyclooctadiene lignans including the new lignans rubrisandrins A (1a + 1b) and B (2) and the known lignans gomisin J (3), (+/-)-gomisin M1 (4), (+)-gomisin M2 (5), schisanhenol (6), deoxyschisandrin, schisantherin B, schisandrin, tigloylgomisin P, gomisin O, angeloylgomisin P, and Epigomisin O. Their structure and stereochemistry were determined by spectroscopic methods, including 2D-NMR techniques.
Compounds 1 and 3-6 were active as anti-HIV agents. (+/-)-Gomisin M1 (4) exhibited the most potent anti-HIV activity, with EC50 and therapeutic index (TI) values of <0.65 microM and >68, respectively.
Epigomisin O Description
||The fruits of Schizandra chinensis
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.PMID: 29328914
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.PMID: 29149595
Scientific Reports 2017 Dec 11;7(1):17332.doi: 10.1038/s41598-017-17427-6.PMID: 29230013
Molecules. 2017 Oct 27;22(11). pii: E1829.doi: 10.3390/molecules22111829.PMID: 29077044
J Cell Biochem. 2018 Feb;119(2):2231-2239.doi: 10.1002/jcb.26385. PMID: 28857247
Phytomedicine. 2018 Feb 1;40:37-47. doi:10.1016/j.phymed.2017.12.030PMID: 29496173
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
|Chem Pharm Bull (Tokyo). 2007 Aug;55(8):1281-3. |
|Lignans from Schisandra propinqua var. propinqua.[Pubmed: 17666862]|
METHODS AND RESULTS:
Two new dibenzocyclooctadiene lignans angeloyl-(+)-gomisin K(3) (1) and methylisogomisin O (2), together with six known ones, isogomisin O, angeloylisogomisin O, gomisin O, angeloygomisin O, benzoylgomisin O, Epigomisin O, and four 1,4-bis(phenyl)-2,3-dimethylbutane type lignans, pregomisin, meso-dihydroguaiaretic acid, isoanwulignan, and sphenanlignan were isolated from the aerial parts of Schisandra propinqua var. propinqua.
The structures of 1 and 2 were elucidated by spectroscopic methods including extensive 1D- and 2D-NMR techniques.