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Euparone
Euparone
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Euparone
Price:
CAS No.: 53947-86-7
Catalog No.: CFN96898
Molecular Formula: C12H10O4
Molecular Weight: 218.20 g/mol
Purity: >=98%
Type of Compound: Phenols
Physical Desc.: Powder
Source: The rhizomes of Eupatorium purpureum.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
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  • University of Bonn (Germany)
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Related Screening Libraries
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10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Eupatarone is a natural product from Eupatorium sternbergianum.
In vitro:
Phytother Res. 2001 Dec;15(8):687-90.
Antiinflammatory activity of the antirheumatic herbal drug, gravel root (Eupatorium purpureum): further biological activities and constituents.[Pubmed: 11746861]
Previous reports from this laboratory revealed that cistifolin from the antirheumatic herbal drug, gravel root (rhizome of Eupatorium purpureum), showed activity both in in vitro and in vivo models of inflammation.
METHODS AND RESULTS:
Data are now presented to show that, in addition to the LFA-1 and other integrin-mediated leucocyte adhesions, cistifolin inhibits the Mac-1 (CD11b/CD18)-dependent monocyte adhesion to fibrinogen in a concentration-dependent manner. Further phytochemical analysis of the crude extract also led to the isolation of three known benzofurans, euparin, Euparone, 6-hydroxy-3beta-methoxytrematone and a new benzofuran, 5-acetyl-6-hydroxy-2-(1-oxo-2-acetoxy-ethyl)-benzofuran.
CONCLUSIONS:
None of these compounds were active in suppressing integrin-mediated monocytic U937 cell adhesions in vitro.
Euparone Description
Source: The rhizomes of Eupatorium purpureum.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
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IF=13.297(2019)

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IF=12.804(2019)

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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.583 mL 22.9148 mL 45.8295 mL 91.659 mL 114.5738 mL
5 mM 0.9166 mL 4.583 mL 9.1659 mL 18.3318 mL 22.9148 mL
10 mM 0.4583 mL 2.2915 mL 4.583 mL 9.1659 mL 11.4574 mL
50 mM 0.0917 mL 0.4583 mL 0.9166 mL 1.8332 mL 2.2915 mL
100 mM 0.0458 mL 0.2291 mL 0.4583 mL 0.9166 mL 1.1457 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Cinnamic aldehyde

Catalog No: CFN90321
CAS No: 14371-10-9
Price: $30/20mg
Trilobatin

Catalog No: CFN98658
CAS No: 4192-90-9
Price: $30/20mg
Linolenic acid

Catalog No: CFN70110
CAS No: 463-40-1
Price: $30/20mg
N1,N10-Bis(p-coumaroyl)spermidine

Catalog No: CFN99248
CAS No: 114916-05-1
Price: $ /
Demethylzeylasteral

Catalog No: CFN90136
CAS No: 107316-88-1
Price: $40/20mg
Cryptotanshinone

Catalog No: CFN98478
CAS No: 35825-57-1
Price: $30/20mg
Neomangiferin

Catalog No: CFN98122
CAS No: 64809-67-2
Price: $80/20mg
Rosmarinyl glucoside

Catalog No: CFN95297
CAS No: 910028-78-3
Price: $413/5mg
Isosilybin B

Catalog No: CFN91071
CAS No: 142796-22-3
Price: $238/5mg
4'-Hydroxywogonin

Catalog No: CFN98960
CAS No: 57096-02-3
Price: $268/10mg
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