ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
How to Order
Orders via your E-mail:
1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Sent to Email: firstname.lastname@example.org
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Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
Delivery & Payment method
1. Usually delivery time: Next day delivery by 9:00 a.m. Order now
2. We accept: Wire transfer & Credit card & Paypal & Western Union
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
More articles cited ChemFaces products.
International Journal of Mol. Med.2015 Mar 6.Korean J. of Horticultural Sci. & Tech. No.2, 2017.2Industrial Crops and Products2017 Jan.Journal of Functional FoodsFeb. 2018;Lab On a Chip21 Feb 2018;
Acta Pharmaceutica Sinica B2015 Apr.7.Phytomedicine1 March 2018;Scientific Reports2015 August 26 J Breast Cancer2015 Jun;18(2):112-118.Universidade Estadual Paulista2017;
JPCMarch 16, 2017J Chromatogr Sci.2015 Feb 5. pii: bmu231. Int J Mol Med.2015 Dec 28.J of L. Chroma. & Related Tech2017 Apr 21;
Our products had been exported to the following research institutions and universities, And still growing.
University of Illinois (USA)CSIRO - Agriculture Flagship (Australia)University of Leipzig (Germany)Medical University of Gdansk (Poland)
National Hellenic Research Found... (Greece)University of Helsinki (Finland)Centralised Purchases Unit (CPU)... (India)Monash University Sunway Campus (Malaysia)
National Cancer Center Research ... (Japan)Uniwersytet Jagielloński w Krak... (Poland)University of Queensland (Australia)
||Fuziline shows significant insecticidal activity against Nilaparvata legen and Aphis medicagini. Fuziline shows activity against pentobarbital sodiuminduced cardiomyocytes damage by obviously recovering beating rhythm and increasing the cell viability.|
|Molecules, 2012, 17(8):9939-46. |
|Alkaloids isolated from the lateral root of Aconitum carmichaelii.[Pubmed: 22907155 ]|
|Two new alkaloids, aconicarmine (1) and aconicaramide (5), were isolated from the EtOH extract of the lateral roots of Aconitum carmichaelii, together with five known compounds: Fuziline (2), neoline (3), N-ethylhokbusine B (4), 5-hydroxymethylpyrrole-2-carbaldehyde (6), and oleracein E (7). |
METHODS AND RESULTS:
Their structures were elucidated by physical and NMR analysis. Pyrrole alkaloids were isolated from A. carmichaelii for the first time. In the in vitro assays, compounds 2 and 3 showed activity against pentobarbital sodiuminduced cardiomyocytes damage by obviously recovering beating rhythm and increasing the cell viability, while compounds 5 and 7 showed moderate antibacterial activity.
|《Pharmacy and Clinics of Chinese Materia Medica》 2014-03 |
|The pharmacological research progress of Fuziline and Neoline[Reference: WebLink]|
|By analyzing and summarizing pharmacological research literature about Fuziline and Neoline,the pharmacological research of both drugs are found to be mainly concentrated on the cardiovascular system,analgesia,anesthesia,antitumor,insecticidal,and so on.At the same time,Fuziline and Neoline are lack of a comprehensive and systematic pharmacological research.|
|Biomed Chromatogr. 2014 Dec;28(12):1707-13. |
|Development and validation of a UHPLC-qTOF-MS method for quantification of fuziline in rat plasma and its application in a pharmacokinetic study.[Pubmed: 24782408]|
METHODS AND RESULTS:
A specific and sensitive UHPLC-qTOF-MS method was developed and validated for quantification of Fuziline in rat plasma after oral administration of three dosages. The analyte was separated on an Acquity UPLC BEH C18 column with a total running time of 3 min using a mobile phase of 0.1% formic acid aqueous solution and methanol (80:20, v/v) at a flow-rate of 0.25 mL/min. The calibration curves for Fuziline showed good linearity in the concentrations ranging from 1 to 200 ng/mL with correlation coefficients >0.997. The precision, accuracy, recovery and stability were deemed acceptable. The method was applied to a pharmacokinetics study of Fuziline in rats. The mean half-life was 5.93, 6.13 and 5.12 h for 1, 2 and 4 mg/kg oral administration of Fuziline, respectively. The peak concentration and area under the concentration-time curve increased linearly with the doses.
The sum of these results indicated that, in the range of the doses examined, the pharmacokinetics of Fuziline in rat was based on first-order kinetics.
||The roots of Aconitum carmichaeli Debx.
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.PMID: 29328914
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.PMID: 29149595
Scientific Reports 2017 Dec 11;7(1):17332.doi: 10.1038/s41598-017-17427-6.PMID: 29230013
Molecules. 2017 Oct 27;22(11). pii: E1829.doi: 10.3390/molecules22111829.PMID: 29077044
J Cell Biochem. 2018 Feb;119(2):2231-2239.doi: 10.1002/jcb.26385. PMID: 28857247
Phytomedicine. 2018 Feb 1;40:37-47. doi: 10.1016/j.phymed.2017.12.030.PMID: 29496173
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.