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Gelsempervine A
Gelsempervine A
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Gelsempervine A
Price:
CAS No.: 865187-17-3
Catalog No.: CFN96018
Molecular Formula: C22H26N2O4
Molecular Weight: 382.5 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The herbs of Gelsemium elegans
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
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Biological Activity
Description: Gelsempervine A is a natural product from Gelsemium elegans.
Gelsempervine A Description
Source: The herbs of Gelsemium elegans
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.6144 mL 13.0719 mL 26.1438 mL 52.2876 mL 65.3595 mL
5 mM 0.5229 mL 2.6144 mL 5.2288 mL 10.4575 mL 13.0719 mL
10 mM 0.2614 mL 1.3072 mL 2.6144 mL 5.2288 mL 6.5359 mL
50 mM 0.0523 mL 0.2614 mL 0.5229 mL 1.0458 mL 1.3072 mL
100 mM 0.0261 mL 0.1307 mL 0.2614 mL 0.5229 mL 0.6536 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Symposium on the chemistry of natural products, 2006 (48) :319-324.
New Indole Alkaloids from Gelsemium Plants and their Cytotoxic Activity on Tumor Cells[Reference: WebLink]
Gelseiridone (10) is a new type of alkaloid having a nitrogen-carbon linkage between a gelsenicine-type monoterpenoid indole alkaloid that possesses an α,β-unsaturated ketone residue as well as the N_b-C20 seco-form and a monoterpene unit having an iridoid skeleton.
METHODS AND RESULTS:
Five new sarpagine-type alkaloids, Gelsempervine A (23), gelsempervine B (24), gelsempervine C (25), and gelsempervine D (26), and 19Z-16-epi-voacarpine (27), and one yohimbane-type alkaloid, sempervilam (29) were isolated from G. sempervirens.
CONCLUSIONS:
Spectroscopic data suggest that 23 existed as a C/D ring-opening structure with the keto-amine form (A) in such aprotic solvents as CH3CN, and as a transannular structure with the zwitterionic form (B) in such protic solvents as CH3OH.
Orobol

Catalog No: CFN98737
CAS No: 480-23-9
Price: $ /
Sinapine thiocyanate

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CAS No: 7431-77-8
Price: $50/20mg
Tannic acid

Catalog No: CFN90501
CAS No: 1401-55-4
Price: $40/20mg
Ganoderic acid F

Catalog No: CFN92055
CAS No: 98665-15-7
Price: $318/20mg
Proline

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CAS No: 147-85-3
Price: $30/20mg
Aconitine

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CAS No: 302-27-2
Price: $80/20mg
Schizandrin C

Catalog No: CFN99708
CAS No: 61301-33-5
Price: $128/20mg
alpha-Viniferin

Catalog No: CFN97068
CAS No: 62218-13-7
Price: $318/10mg
L-Phenylalanine

Catalog No: CFN93152
CAS No: 63-91-2
Price: $30/20mg
Iridin

Catalog No: CFN96557
CAS No: 491-74-7
Price: $50/20mg
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