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    Gomisin L1
    Gomisin L1
    Information
    CAS No. 82425-43-2 Price
    Catalog No.CFN96734Purity>=98%
    Molecular Weight386.44Type of CompoundLignans
    FormulaC22H26O6Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)
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    Biological Activity
    Description: 1. (-)-Gomisin L1 induces G2/M arrest and apoptosis in human ovarian cancer cells.
    Gomisin L1 Description
    Source: The fruits of Schizandra chinensis BAILL.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.

    PMID: 29328914

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.

    PMID: 29149595

    Scientific Reports 2017 Dec 11;7(1):17332.
    doi: 10.1038/s41598-017-17427-6.

    PMID: 29230013

    Molecules. 2017 Oct 27;22(11). pii: E1829.
    doi: 10.3390/molecules22111829.

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    J Cell Biochem. 2018 Feb;119(2):2231-2239.
    doi: 10.1002/jcb.26385.

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    Phytomedicine. 2018 Feb 1;40:37-47.
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    PMID: 29496173
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.5877 mL 12.9386 mL 25.8772 mL 51.7545 mL 64.6931 mL
    5 mM 0.5175 mL 2.5877 mL 5.1754 mL 10.3509 mL 12.9386 mL
    10 mM 0.2588 mL 1.2939 mL 2.5877 mL 5.1754 mL 6.4693 mL
    50 mM 0.0518 mL 0.2588 mL 0.5175 mL 1.0351 mL 1.2939 mL
    100 mM 0.0259 mL 0.1294 mL 0.2588 mL 0.5175 mL 0.6469 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Gomisin L1 References Information
    Citation [1]

    International Journal of Molecular Medicine, 2015, 36:S57-S57.

    (-)-Gomisin L1 isolated from Schisandra Chinensis fruit induces G2/M arrest and apoptosis in human ovarian cancer cells[Reference: WebLink]
    (-)-Gomisin L1 isolated from Schisandra Chinensis fruit induces G2/M arrest and apoptosis in human ovarian cancer cells.
    Citation [2]

    Chemical & Pharmaceutical Bulletin, 1982, 30(1):132-139

    The Constituents of Schizandra chinensis Baill. X. The Structures of .GAMMA.-schizandrin and four new lignans,(-)-gomisins L1 and L2,(.+-.)-gomisin M1 and (+)-gomisin M2.[Reference: WebLink]
    Four new dibenzocyclooctadiene lignans, named (-)-Gomisin L1 (6) and (-)-gomisin L2 (7), (±)-gomisin M1 (8) and (+)-gomisin M2 (9), were isolated from the fruits of Schizandra chinensis BAILL. (Schizandraceae). Their absolute structures were elucidated by means of chemical and spectral studies. The stereostructure of γ-schizandrin (1, dl-form), the plane structure of which had already been suggested by Kochetkov et al. and Liu et al., was also elucidated on the basis of chemical and spectral studies.