Science | Nature | Cell | View More
Natural Products
Homaloside D
Homaloside D
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Homaloside D
Price:
CAS No.: 149155-19-1
Catalog No.: CFN99617
Molecular Formula: C27H28O12
Molecular Weight: 544.5 g/mol
Purity: >=98%
Type of Compound: Phenols
Physical Desc.: Powder
Source: The herbs of Gynocardia odorata
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • Leibniz-Institut für Pflanzenb... (Germany)
  • University of Padjajaran (Indonesia)
  • Universidade Federal de Goias (... (Brazil)
  • University of Oslo (Norway)
  • Tohoku University (Japan)
  • Universitas islam negeri Jakarta (Indonesia)
  • University of Canterbury (New Zealand)
  • Ain Shams University (Egypt)
  • University of Brasilia (Brazil)
  • Sant Gadge Baba Amravati Univer... (India)
  • University of Illinois at Chicago (USA)
  • More...
Package
Featured Products
Mangiferin

Catalog No: CFN98719
CAS No: 4773-96-0
Price: $40/20mg
Proanthocyanidins

Catalog No: CFN99556
CAS No: 4852-22-6
Price: $70/20mg
Kaempferol 3-O-arabinoside

Catalog No: CFN97572
CAS No: 99882-10-7
Price: $338/5mg
Alisol C

Catalog No: CFN92545
CAS No: 30489-27-1
Price: $318/5mg
5'-Guanylic acid

Catalog No: CFN91721
CAS No: 85-32-5
Price: $30/20mg
Oleuropein

Catalog No: CFN98416
CAS No: 32619-42-4
Price: $30/20mg
Ginsenoside MC

Catalog No: CFN95232
CAS No: 175484-06-7
Price: $318/10mg
(+)-Epipinoresinol

Catalog No: CFN92288
CAS No: 24404-50-0
Price: $338/5mg
Eleutheroside E

Catalog No: CFN99984
CAS No: 39432-56-9
Price: $50/20mg
Fraxetin

Catalog No: CFN99113
CAS No: 574-84-5
Price: $30/20mg
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Homaloside D has antiplasmodial activity.
Targets: Antifection
In vitro:
J Ethnopharmacol. 2010 Jul 20;130(2):272-4.
Antimalarial compounds from the aerial parts of Flacourtia indica (Flacourtiaceae).[Pubmed: 20457242]
In the Comoros Islands, the aerial parts of Flacourtia indica are used in traditional medicine to treat malaria. Because of the important use of this plant, the phytochemistry of the aerial parts was investigated.
METHODS AND RESULTS:
Three compounds were isolated from the decoction of this plant material, pyrocatechol, Homaloside D and poliothrysoside. The in vitro antiplasmodial activity on the chloroquine-resistant strain (W2) of Plasmodium falciparum and the cytotoxicity on two complementary human cell lines (THP1, HepG2), of AcOEt extract obtained after liquid/liquid extraction of the decoction and pure compounds, were evaluated. The poliothrysoside isolated from the AcOEt extract presented a strong antiplasmodial activity (IC(50)=7.4 microM) and a good selectivity index (>28) similar to chloroquine.
CONCLUSIONS:
This study reports for the first time antiplasmodial activity for Flacourtia indica, for its AcOEt extract and the three major constituents and confirms its traditional use.
Homaloside D Description
Source: The herbs of Gynocardia odorata
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
New compound 8

Catalog No: CFN95341
CAS No: N/A
Price: $318/5mg
Pilosidine

Catalog No: CFN95110
CAS No: 229971-57-7
Price: $413/5mg
(2S)-5,7,3',4'-tetramethoxyflavano...

Catalog No: CFN95406
CAS No: 74628-43-6
Price: $318/10mg
Columbianetin beta-D-glucopyranosi...

Catalog No: CFN95038
CAS No: 55836-35-6
Price: $288/5mg
Astin C

Catalog No: CFN95189
CAS No: 148057-23-2
Price: $318/10mg
Ampelopsin G

Catalog No: CFN95148
CAS No: 151487-09-1
Price: $318/5mg
Shancigusin I

Catalog No: CFN95061
CAS No: 1435488-35-9
Price: $/mg
Yuanhuanin

Catalog No: CFN95127
CAS No: 83133-14-6
Price: $318/5mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.8365 mL 9.1827 mL 18.3655 mL 36.7309 mL 45.9137 mL
5 mM 0.3673 mL 1.8365 mL 3.6731 mL 7.3462 mL 9.1827 mL
10 mM 0.1837 mL 0.9183 mL 1.8365 mL 3.6731 mL 4.5914 mL
50 mM 0.0367 mL 0.1837 mL 0.3673 mL 0.7346 mL 0.9183 mL
100 mM 0.0184 mL 0.0918 mL 0.1837 mL 0.3673 mL 0.4591 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
J Nat Prod. 1993 May;56(5):699-707.
A phytochemical investigation of Homalium ceylanicum.[Pubmed: 8326319]

METHODS AND RESULTS:
Vacciniin [4] (6-O-benzoyl-D-glucopyranoside) and two new benzenoid glucosides, homaloside A [1] (1''-O-benzyl-3''-O-benzoyl-alpha-L-arabinopyranosyl(1'''-->4'')- beta-D-glucopyranoside) and Homaloside D [2] [1-(1'-hydroxy-6'-oxocyclohex-2'-ene-carboxymethyl)- 5-hydroxyphenyl-6''-O-benzoyl-beta-D-glucopyranoside], were isolated from the n-BuOH fraction of Homalium ceylanicum (Flacourtiaceae). A novel cyclohexenone carboxylic acid ester, 1-hydroxy-6-oxocyclohex-2-enoic acid methyl ester [3], was also isolated from this fraction.
CONCLUSIONS:
The structures were elucidated by chemical and nmr (COLOC, FLOCK, and selective INEPT) techniques.
Mangiferin

Catalog No: CFN98719
CAS No: 4773-96-0
Price: $40/20mg
Proanthocyanidins

Catalog No: CFN99556
CAS No: 4852-22-6
Price: $70/20mg
Kaempferol 3-O-arabinoside

Catalog No: CFN97572
CAS No: 99882-10-7
Price: $338/5mg
Alisol C

Catalog No: CFN92545
CAS No: 30489-27-1
Price: $318/5mg
5'-Guanylic acid

Catalog No: CFN91721
CAS No: 85-32-5
Price: $30/20mg
Oleuropein

Catalog No: CFN98416
CAS No: 32619-42-4
Price: $30/20mg
Ginsenoside MC

Catalog No: CFN95232
CAS No: 175484-06-7
Price: $318/10mg
(+)-Epipinoresinol

Catalog No: CFN92288
CAS No: 24404-50-0
Price: $338/5mg
Eleutheroside E

Catalog No: CFN99984
CAS No: 39432-56-9
Price: $50/20mg
Fraxetin

Catalog No: CFN99113
CAS No: 574-84-5
Price: $30/20mg
Tags: buy Homaloside D | Homaloside D supplier | purchase Homaloside D | Homaloside D cost | Homaloside D manufacturer | order Homaloside D | Homaloside D distributor