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    Homomangiferin
    Information
    CAS No. 21794-66-1 Price
    Catalog No.CFN80148Purity>=98%
    Molecular Weight436.36Type of CompoundXanthones
    FormulaC20H20O11Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)
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    Homomangiferin Description
    Source: The herbs of Mangifera indica
    Biological Activity or Inhibitors: 1. Homomangiferin shows antitumoural effects against MDA-MB-231 cells.
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.

    PMID: 29328914

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.

    PMID: 29149595

    Scientific Reports 2017 Dec 11;7(1):17332.
    doi: 10.1038/s41598-017-17427-6.

    PMID: 29230013

    Molecules. 2017 Oct 27;22(11). pii: E1829.
    doi: 10.3390/molecules22111829.

    PMID: 29077044

    J Cell Biochem. 2018 Feb;119(2):2231-2239.
    doi: 10.1002/jcb.26385.

    PMID: 28857247

    Phytomedicine. 2018 Feb 1;40:37-47.
    doi:10.1016/j.phymed.2017.12.030

    PMID: 29496173
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.2917 mL 11.4584 mL 22.9169 mL 45.8337 mL 57.2921 mL
    5 mM 0.4583 mL 2.2917 mL 4.5834 mL 9.1667 mL 11.4584 mL
    10 mM 0.2292 mL 1.1458 mL 2.2917 mL 4.5834 mL 5.7292 mL
    50 mM 0.0458 mL 0.2292 mL 0.4583 mL 0.9167 mL 1.1458 mL
    100 mM 0.0229 mL 0.1146 mL 0.2292 mL 0.4583 mL 0.5729 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Homomangiferin References Information
    Citation [1]

    Food Funct. 2017 Oct 18;8(10):3610-3620.

    Selective antitumoural action of pressurized mango leaf extracts against minimally and highly invasive breast cancer.[Pubmed: 28891568]
    Mango leaf tea has been traditionally used by different cultures to reduce inflammation in the body. There is evidence that chronic inflammation increases the risk of cancer. This study investigates the antitumoural effects of pressurized mango leaf extracts on minimally (MCF7) and highly invasive (MDA-MB-231) breast cancer cells as well as on non-tumourigenic cells (MCF10). Extracts showed protective properties against oxidation and cytotoxic effects against breast cancer cell lines, causing minor damage to non-carcinogenic cells. Nonetheless, some selective activity, depending on hormone receptor status, was observed. This was possibly related to the presence of minor compounds. Extracts with high levels of gallotannins showed cytotoxic action against MCF7 cells, while those which had methyl gallate and Homomangiferin as common components were more effective against MDA-MB-231 cells. Therefore, the cytotoxic effect of mango leaf extracts might be attributed to the synergistic effect of different polyphenols and not just to mangiferin on its own as the predominant compound in mango leaves.