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Isomaculosidine
Isomaculosidine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Isomaculosidine
Price:
CAS No.: 518-96-7
Catalog No.: CFN96765
Molecular Formula: C14H13NO4
Molecular Weight: 259.26 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The root barks of Dictamnus dasycarpus.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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Related Screening Libraries
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10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Isomaculosidine can significantly inhibit nitric oxide (NO) production in lipopolysaccharide (LPS)-stimulated BV2 cells.
Targets: NO
In vitro:
J Enzyme Inhib Med Chem. 2012 Aug;27(4):490-4.
Inhibitory alkaloids from Dictamnus dasycarpus root barks on lipopolysaccharide-induced nitric oxide production in BV2 cells.[Pubmed: 21827366 ]

METHODS AND RESULTS:
The methanolic extract of Dictamnus dasycarpus root barks afforded one new glycosidic quinoline alkaloid, 3-[1β-hydroxy-2-(β-D-glucopyranosyloxy)-ethyl)-4-methoxy-2(1H)-quinolinone (1), together with nine known compounds, preskimmianine (2), 8-methoxy-N-methylflindersine (3), dictamine (4), γ-fagarine (5), halopine (6), skimmianine (7), dictangustine-A (8), iso-γ-fagarine (9), Isomaculosidine (10).
CONCLUSIONS:
The isolated alkaloids significantly inhibited nitric oxide (NO) production in lipopolysaccharide (LPS)-stimulated BV2 cells. Among them, compounds 3 and 7 showed the most potent inhibitory activities on LPS-induced NO production.
Isomaculosidine Description
Source: The root barks of Dictamnus dasycarpus.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.8571 mL 19.2857 mL 38.5713 mL 77.1426 mL 96.4283 mL
5 mM 0.7714 mL 3.8571 mL 7.7143 mL 15.4285 mL 19.2857 mL
10 mM 0.3857 mL 1.9286 mL 3.8571 mL 7.7143 mL 9.6428 mL
50 mM 0.0771 mL 0.3857 mL 0.7714 mL 1.5429 mL 1.9286 mL
100 mM 0.0386 mL 0.1929 mL 0.3857 mL 0.7714 mL 0.9643 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Bornyl acetate

Catalog No: CFN90494
CAS No: 5655-61-8
Price: $30/20mg
Chebulagic acid

Catalog No: CFN92295
CAS No: 23094-71-5
Price: $ / mg
Pulegone

Catalog No: CFN93286
CAS No: 89-82-7
Price: $30/20mg
Rebaudioside F

Catalog No: CFN95215
CAS No: 438045-89-7
Price: $268/5mg
Corydaline

Catalog No: CFN90196
CAS No: 518-69-4
Price: $138/20mg
Oxypaeoniflorin

Catalog No: CFN99589
CAS No: 39011-91-1
Price: $138/20mg
Cineole

Catalog No: CFN90545
CAS No: 470-82-6
Price: $30/20mg
p-Cymene

Catalog No: CFN70239
CAS No: 99-87-6
Price: $30/20mg
Nerolidol

Catalog No: CFN98638
CAS No: 7212-44-4
Price: $30/20mg
Kaempferol 3,7-di-O-glucoside

Catalog No: CFN91159
CAS No: 25615-14-9
Price: $288/5mg
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