Kadsurin A | CAS:99340-07-5 | Manufacturer ChemFaces

Kadsurin A

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Kadsurin A Description

Source:	The fruits of Kadsura longipedunculata
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Structure Identification:

Pharmacol Res Commun. 1986 Aug;18 Suppl:25-32.

Crystal and molecular structure of BN 52021, a PAF-acether antagonist. Comparison with the conformation of Kadsurenone and related compounds.[Pubmed: 3774849]

METHODS AND RESULTS:
BN52021 (Ginkgolide B) monohydrate C20H24O10 X H2O crystallizes in the triclinic space group P1 with two independant molecules in the unit cell of which parameters are a = 7.627(2), b = 11.514(3), c = 12.941(3)A, alpha = 97.05(2), beta = 90.27(2) and gamma = 108.71(2)o, V = 1067.06A3. Calculated density Dx = 1.320g X cm-3. The crystal structure was solved by Patterson methods starting from dreiding model data. The final reliability index R = 0.099 for 3848 observed reflections collected with a four-circle diffractometer.
CONCLUSIONS:
Anti-PAF activities of Kadsurenone, Kadsurin A, Kadsurin B and Piperenone, molecular structure of MIRANDIN-A, related compounds and BN52021 suggest that a distance 0-0 of about 6.6A observed in Kadsurenone and in BN52021 could be favourable to anti-PAF activity.

Product Name	Kadsurin A
Price:
CAS No.:	99340-07-5
Catalog No.:	CFN96250
Molecular Formula:	C₂₁H₂₄O₆
Molecular Weight:	372.4 g/mol
Purity:	>=98%
Type of Compound:	Lignans
Physical Desc.:	Oil
Source:	The fruits of Kadsura longipedunculata
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Anti-platelet aggregation Compound Library Lignans Compound Library PAFR Inhibitor Library

Description:	Kadsurin A and Kadsurin B have anti-platelet activating factor activities.
Targets:	PAFR

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.6853 mL	13.4264 mL	26.8528 mL	53.7057 mL	67.1321 mL
5 mM	0.5371 mL	2.6853 mL	5.3706 mL	10.7411 mL	13.4264 mL
10 mM	0.2685 mL	1.3426 mL	2.6853 mL	5.3706 mL	6.7132 mL
50 mM	0.0537 mL	0.2685 mL	0.5371 mL	1.0741 mL	1.3426 mL
100 mM	0.0269 mL	0.1343 mL	0.2685 mL	0.5371 mL	0.6713 mL

CFN96400	Isodihydrofutoquinol B	62499-71-2	356.4	C₂₁H₂₄O₅
CFN96401	Isodihydrofutoquinol A	62560-95-6	356.4	C₂₁H₂₄O₅
CFN96245	Fargesone A	116424-69-2	372.4	C₂₁H₂₄O₆
CFN96260	Fargesone B	116424-70-5	372.4	C₂₁H₂₄O₆
CFN96289	1,6-Dihydro-4,7'-epoxy-1-methoxy-3',4'-methylenedioxy-6-oxo-3,8'-lignan	67920-48-3	340.4	C₂₀H₂₀O₅
CFN96311	(2S)-2alpha-(1,3-Benzodioxol-5-yl)-3,5-dihydro-5alpha-methoxy-3beta-methyl-5-allyl-2H-benzofuran-6-one	57430-03-2	340.4	C₂₀H₂₀O₅
CFN96250	Kadsurin A	99340-07-5	372.4	C₂₁H₂₄O₆
CFN96283	Piperenone	57625-31-7	388.5	C₂₂H₂₈O₆
CFN96286	Mirandin B	62163-24-0	386.4	C₂₂H₂₆O₆
CFN96386	Burchellin	38276-59-4	340.4	C₂₀H₂₀O₅