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    Lethedoside A
    Information
    CAS No. 221289-20-9 Price
    Catalog No.CFN98100Purity>=98%
    Molecular Weight490.5 Type of CompoundFlavonoids
    FormulaC24H26O11Physical DescriptionPowder
    Download Manual    COA    MSDSSimilar structuralComparison (Web)
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    Our products had been exported to the following research institutions and universities, And still growing.
  • University of Liège (Belgium)
  • Universidad Industrial de Santan... (Colombia)
  • Regional Crop Research Institute (Korea)
  • Massachusetts General Hospital (USA)
  • Deutsches Krebsforschungszentrum (Germany)
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    Biological Activity
    Description: Lethedoside A has inactive or weakly active against KB tumor cells.
    Lethedoside A Description
    Source: The herbs of Aquilaria sinensis
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.

    PMID: 29328914

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.

    PMID: 29149595

    Scientific Reports 2017 Dec 11;7(1):17332.
    doi: 10.1038/s41598-017-17427-6.

    PMID: 29230013

    Molecules. 2017 Oct 27;22(11). pii: E1829.
    doi: 10.3390/molecules22111829.

    PMID: 29077044

    J Cell Biochem. 2018 Feb;119(2):2231-2239.
    doi: 10.1002/jcb.26385.

    PMID: 28857247

    Phytomedicine. 2018 Feb 1;40:37-47.
    doi:10.1016/j.phymed.2017.12.030

    PMID: 29496173
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.0387 mL 10.1937 mL 20.3874 mL 40.7747 mL 50.9684 mL
    5 mM 0.4077 mL 2.0387 mL 4.0775 mL 8.1549 mL 10.1937 mL
    10 mM 0.2039 mL 1.0194 mL 2.0387 mL 4.0775 mL 5.0968 mL
    50 mM 0.0408 mL 0.2039 mL 0.4077 mL 0.8155 mL 1.0194 mL
    100 mM 0.0204 mL 0.1019 mL 0.2039 mL 0.4077 mL 0.5097 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    J Nat Prod. 1999 Feb;62(2):241-3.
    Five new flavone 5-O-glycosides from Lethedon tannaensis: lethedosides and lethediosides.[Pubmed: 10075750]

    METHODS AND RESULTS:
    Five new 7-methoxy-flavone 5-O-glycosides were isolated from a cytotoxic MeOH extract of Lethedon tannaensis, and the structures were elucidated by 2D NMR spectral analysis and by chemical methods. Lethedosides A (1), B (2), and C (3) were 5-O-glucosides of 7,3', 4'-tri-O-methylluteolin, 7,3',4',5'-tetra-O-methyltricetin, and 7,3', 4'-tri-O-methytricetin, respectively; Lethedoside A (4) and B (5) and a known compound 6 were 5-O-xylosylglucosides of 7,3', 4'-tri-O-methylluteolin, 7,3',4',5'-tetra-O-methyltricetin, and 7, 4'-di-O-methylapigenin, respectively.
    CONCLUSIONS:
    These flavonoids were either inactive or weakly active against KB tumor cells, in contrast to previously isolated flavones from the same plant.