ChemFaces is a professional high-purity natural products manufacturer.
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1. Reference standards
2. Pharmacological research
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More articles cited ChemFaces products.
Phytomedicine. 2017 Jan 15;Neuropharmacology.2018 Mar 15;Arch Biochem Biophys. 2018 Jan 15;Institute of Materia Medica2016 Mar 31, pp.29-35Int J Mol Med.2015 Dec 28.
Int J Mol Sci. 2014 May 13;15(5):8443-57.Inflammation.2015 Feb;38(1):445-55. J Sep Sci.2018 Jan 23.Food and Bioprocess TechnologyJune 2017J. of Food Composition & Analysis2017
Chem Biol Interact.2018 Mar 1;BangaloreOct/Dec 2017;J Nat Med.2017 AprJ Breast Cancer2015 Jun;18(2):112-118.
Our products had been exported to the following research institutions and universities, And still growing.
Regional Crop Research Institute (Korea)Nanjing University of Chinese Me... (China)University of Brasilia (Brazil)Colorado State University (USA)
Charles University in Prague (Czech Republic)Universidade do Porto (Portugal)The Vancouver Prostate Centre (V... (Canada)Univerzita Karlova v Praze (Czech Republic)
Copenhagen University (Denmark)University of Zurich (Switzerland)Semmelweis Unicersity (Hungary)
|| Linderene, linderalactone and isolinderalactone inhibit the enzymes from both origins to the same extent. |
||The roots of Lindera aggregata( Sims) Kosterm
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.PMID: 29328914
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.PMID: 29149595
Scientific Reports 2017 Dec 11;7(1):17332.doi: 10.1038/s41598-017-17427-6.PMID: 29230013
Molecules. 2017 Oct 27;22(11). pii: E1829.doi: 10.3390/molecules22111829.PMID: 29077044
J Cell Biochem. 2018 Feb;119(2):2231-2239.doi: 10.1002/jcb.26385. PMID: 28857247
Phytomedicine. 2018 Feb 1;40:37-47. doi:10.1016/j.phymed.2017.12.030PMID: 29496173
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
|Biol Pharm Bull. 2002 Aug;25(8):1049-52. |
|Prolyl endopeptidase inhibitors from the roots of Lindera strychnifolia F. Vill.[Pubmed: 12186408]|
|We studied the PEP inhibitory constituents of the roots of Lindera strychnifolia F. VILL and isolated two known tannins, epicatechin (1) and aesculitannin B (2), and four known sesquiterpenes, Linderene (3), Linderene acetate (4), linderalactone (5) and isolinderalactone (6) as inhibitors.
METHODS AND RESULTS:
On the inhibitory activities of six compounds against PEP from Flavobacterium meningosepticum and that from rat brain supernatant, compounds 1, 2 and Linderene acetate inhibited the enzyme from Flavobacterium more strongly than that from rat brain supernatant. However, Linderene, linderalactone and isolinderalactone inhibited the enzymes from both origins to the same extent and furthermore, compound 6 was the strongest natural inhibitor against PEP from rat brain supernatant.
The kinetic study of these inhibitors indicated that compounds 1, 2 are noncompetitive inhibitors and compounds Linderene,linderalactone,isolinderalactone are competitive inhibitors.