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Macamide B
Macamide B
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Macamide B
Price: $158 / 20mg
CAS No.: 74058-71-2
Catalog No.: CFN90843
Molecular Formula: C23H39NO
Molecular Weight: 345.6 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The herbs of Lepidium meyenii Walp
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $46.0 / In-stock
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Reference standards.
In vitro:
Journal of the Science of Food and Agriculture, 2019,99(3):1405-1412.
Two macamide extracts relieve physical fatigue by attenuating muscle damage in mice.[Reference: WebLink]
Macamides, the main active component contained in maca, have attracted increasing attention due to their various bioactivities.
METHODS AND RESULTS:
In this study, crude macamides extract (CME) and purified macamides extract (PME) were prepared by enzyme‐assisted extraction and macroporous resin separation, and anti‐fatigue effects of CME and PME were evaluated in a forced swimming model. The composition analysis results revealed that both CME and PME mainly contain 8 kinds of macamides. Based on the results of weight‐loaded forced swimming test, compared with control group, CME and and PME groups could prolong the exhaustive swimming time, increase the levels of liver glycogen (LG) and muscle glycogen (MG), accelerate the fatty acids oxidation in serum to provide energy, eliminate the accumulation of blood lactic acid (BLA) and blood urea nitrogen (BUN), as well as decrease the serum biomarkers for muscle damage, such as lactate dehydrogenase (LDH) and creatine kinase (CK). In addition, histological analysis indicated that CME and PME attenuated damage of skeletal muscle and myocardium in mice during exercise.
CONCLUSIONS:
Two macamides extracts have a beneficial effect on relieving physical fatigue by attenuating the damage of skeletal muscle and myocardium during exercise, and a better effect was observed in PME group.
Macamide B Description
Source: The herbs of Lepidium meyenii Walp
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.8935 mL 14.4676 mL 28.9352 mL 57.8704 mL 72.338 mL
5 mM 0.5787 mL 2.8935 mL 5.787 mL 11.5741 mL 14.4676 mL
10 mM 0.2894 mL 1.4468 mL 2.8935 mL 5.787 mL 7.2338 mL
50 mM 0.0579 mL 0.2894 mL 0.5787 mL 1.1574 mL 1.4468 mL
100 mM 0.0289 mL 0.1447 mL 0.2894 mL 0.5787 mL 0.7234 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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CAS No: 94596-28-8
Price: $100/20mg
Carnosol

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CAS No: 5957-80-2
Price: $80/20mg
Uridine

Catalog No: CFN97000
CAS No: 58-96-8
Price: $30/20mg
1-Deoxynojirimycin

Catalog No: CFN99933
CAS No: 19130-96-2
Price: $30/20mg
1,5-Dicaffeoylquinic acid

Catalog No: CFN90937
CAS No: 19870-46-3
Price: $138/20mg
(E)-6-O-(p-coumaroyl)scandoside me...

Catalog No: CFN95192
CAS No: 83946-90-1
Price: $218/10mg
Harpagide

Catalog No: CFN98148
CAS No: 6926-08-5
Price: $70/20mg
Cyclo(Pro-Val)

Catalog No: CFN90275
CAS No: 5654-87-5
Price: $238/10mg
Napellonine

Catalog No: CFN90393
CAS No: 509-24-0
Price: $218/20mg
Vincristine

Catalog No: CFN98589
CAS No: 57-22-7
Price: $138/20mg
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