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Mallorepine
Mallorepine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Mallorepine
Price:
CAS No.: 767-98-6
Catalog No.: CFN97248
Molecular Formula: C7H6N2O
Molecular Weight: 134.1 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The roots of Mallotus repandus
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Mallorepine may propably be an intermediate on the biosynthetic pathway from nicotinamide (II) to ricinine (III).
Mallorepine Description
Source: The roots of Mallotus repandus
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
More...

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 7.4571 mL 37.2856 mL 74.5712 mL 149.1424 mL 186.428 mL
5 mM 1.4914 mL 7.4571 mL 14.9142 mL 29.8285 mL 37.2856 mL
10 mM 0.7457 mL 3.7286 mL 7.4571 mL 14.9142 mL 18.6428 mL
50 mM 0.1491 mL 0.7457 mL 1.4914 mL 2.9828 mL 3.7286 mL
100 mM 0.0746 mL 0.3729 mL 0.7457 mL 1.4914 mL 1.8643 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Planta Med 1978; 33(4): 385-388.
Mallorepine, Cyano–γ–Pyridone from Mallotus repandus[Reference: WebLink]

METHODS AND RESULTS:
The methanol extract of a Formosan folklore drug, the aerial part of Mallotus répandus (Euphorbiaceae), has been fractionated monitored by the antiulcerogenic activity to give, together with bergenin as one of the active principles, a crystalline substance for which the name Mallorepine is given.
CONCLUSIONS:
Mallorepine has been identified as 3–cyano–1–methyl–4–pyridone (I) but has been shown to be inactive in inhibiting the formation of the stress–induced gastric ulcers. Mallorepine may propably be an intermediate on the biosynthetic pathway from nicotinamide (II) to ricinine (III).
CFN892401-Hydroxyacridone65582-54-9211.22C13H9NO2
CFN969731,7-Dihydroxyacridone112649-95-3227.21C13H9NO3
CFN892681-Hydroxy-N-methylacridone16584-54-6225.24C14H11NO2
CFN992971,3-Dihydroxy-4-methoxy-10-methylacridin-9(10H)-one1189362-86-4271.3 C15H13NO4
CFN89147Arborinine5489-57-6285.29C16H15NO4
CFN89259Rutacridone17948-33-3307.34C19H17NO3
CFN99672Sambutoxin160047-56-3453.6 C28H39NO4
CFN980941-Methyl-2-pentyl-4(1H)-quinolinone22048-98-2229.3 C15H19NO
CFN97283Schinifoline80554-58-1257.4 C17H23NO
CFN962901-Methyl-2-nonylquinolin-4(1H)-one68353-24-2285.4C19H27NO
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