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Meliasenin B
Meliasenin B
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Meliasenin B
Price:
CAS No.: 1221262-77-6
Catalog No.: CFN99339
Molecular Formula: C30H44O4
Molecular Weight: 468.7 g/mol
Purity: >=98%
Type of Compound: Triterpenoids
Physical Desc.: Powder
Source: The seeds of Melia azedarach L.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Meliasenin B may cause hepatotoxicity, it displays dose-dependent toxicity on HepG2 cells.
In vitro:
Zhongguo Zhong Yao Za Zhi. 2013 Jun;38(11):1820-2.
[Study on rapid screening and identifying hepatotoxic compounds in toosendan fructus].[Pubmed: 24010303]

METHODS AND RESULTS:
Fluorescein diacetate-labeled HepG2 cells model and flouresence automatic microscopy screening assay were used for fast screening 23 components from Toosendan Fructus, in which 5 components showed significant toxicity on HepG2 cells. The 10 compounds in the 2 components were tentatively identified with LC-MS(n), and 3 of them (Meliasenin B, trichilinin D and 1-O-tigloy-1-O-debenzoylohchinal) were prepared and identified.
CONCLUSIONS:
Further experiments showed that the 3 compounds displayed dose-dependent toxicity on HepG2 cells, suggesting that these compounds in Toosendan Fructus may cause hepatotoxicity.
Meliasenin B Description
Source: The seeds of Melia azedarach L.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.1336 mL 10.6678 mL 21.3356 mL 42.6712 mL 53.339 mL
5 mM 0.4267 mL 2.1336 mL 4.2671 mL 8.5342 mL 10.6678 mL
10 mM 0.2134 mL 1.0668 mL 2.1336 mL 4.2671 mL 5.3339 mL
50 mM 0.0427 mL 0.2134 mL 0.4267 mL 0.8534 mL 1.0668 mL
100 mM 0.0213 mL 0.1067 mL 0.2134 mL 0.4267 mL 0.5334 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
2,4-Dihydroxybenzoic acid

Catalog No: CFN70215
CAS No: 89-86-1
Price: $30/20mg
3-Isomangostin

Catalog No: CFN99724
CAS No: 19275-46-8
Price: $168/10mg
Wogonin

Catalog No: CFN97089
CAS No: 632-85-9
Price: $30/20mg
10-Shogaol

Catalog No: CFN92300
CAS No: 36752-54-2
Price: $138/20mg
Danshensu

Catalog No: CFN99539
CAS No: 22681-72-7
Price: $70/20mg
L-Menthol

Catalog No: CFN98123
CAS No: 2216-51-5
Price: $30/20mg
Stevioside

Catalog No: CFN99548
CAS No: 57817-89-7
Price: $40/20mg
Isobavachin

Catalog No: CFN98400
CAS No: 31524-62-6
Price: $138/20mg
Tilianin

Catalog No: CFN92764
CAS No: 4291-60-5
Price: $218/20mg
Zederone

Catalog No: CFN92616
CAS No: 7727-79-9
Price: $278/20mg
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