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    Methyl tanshinonate
    Information
    CAS No. 18887-19-9 Price
    Catalog No.CFN90411Purity>=98%
    Molecular Weight338.35Type of CompoundDiterpenoids
    FormulaC20H18O5Physical DescriptionRed powder
    Download Manual    COA    MSDS    SDFSimilar structuralComparison
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    Methyl tanshinonate Description
    Source: The roots of Salvia miltiorrhiza
    Biological Activity or Inhibitors: 1. Methyl tanshinonate has antioxidant activity.
    2. Methyl tanshinonate can treat psoriasis.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.9555 mL 14.7776 mL 29.5552 mL 59.1104 mL 73.888 mL
    5 mM 0.5911 mL 2.9555 mL 5.911 mL 11.8221 mL 14.7776 mL
    10 mM 0.2956 mL 1.4778 mL 2.9555 mL 5.911 mL 7.3888 mL
    50 mM 0.0591 mL 0.2956 mL 0.5911 mL 1.1822 mL 1.4778 mL
    100 mM 0.0296 mL 0.1478 mL 0.2956 mL 0.5911 mL 0.7389 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Methyl tanshinonate References Information
    Citation [1]

    Planta Med. 2011 Sep;77(14):1594-6.

    Antiplasmodial and antitrypanosomal activity of tanshinone-type diterpenoids from Salvia miltiorrhiza.[Pubmed: 21412700 ]
    Subsequent isolation and structure elucidation yielded the known substances miltirone (1), tanshinone II a (2), 1,2 dihydrotanshinquinone (3), methylenetanshinquinone (4), 1-oxomiltirone (5), 11-hydroxymiltiodiol (6), tanshinone I (7), Methyl tanshinonate (8), and cryptotanshinone (9). The IC₅₀s of the compounds were determined against the two parasites and rat myoblast (L6) cells. They ranged from 4.1 µM to over 30 µM against P. falciparum K1 strain with selectivity indices (SI) from 0.3 to 1.9. IC₅₀s against T. brucei rhodesiense STIB 900 were from 0.5 µM (1, 4) to over 30 µM, and 4 showed the greatest selective activity with an SI of 24.