|Source:||The roots of Salvia miltiorrhiza|
|Biological Activity or Inhibitors:||1. Methyl tanshinonate has antioxidant activity.
2. Methyl tanshinonate can treat psoriasis.
|Solvent:||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.|
|Storage:||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
|After receiving:||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.|
|1 mg||5 mg||10 mg||20 mg||25 mg|
|1 mM||2.9555 mL||14.7776 mL||29.5552 mL||59.1104 mL||73.888 mL|
|5 mM||0.5911 mL||2.9555 mL||5.911 mL||11.8221 mL||14.7776 mL|
|10 mM||0.2956 mL||1.4778 mL||2.9555 mL||5.911 mL||7.3888 mL|
|50 mM||0.0591 mL||0.2956 mL||0.5911 mL||1.1822 mL||1.4778 mL|
|100 mM||0.0296 mL||0.1478 mL||0.2956 mL||0.5911 mL||0.7389 mL|
Planta Med. 2011 Sep;77(14):1594-6.
|Antiplasmodial and antitrypanosomal activity of tanshinone-type diterpenoids from Salvia miltiorrhiza.[Pubmed: 21412700 ]|
|Subsequent isolation and structure elucidation yielded the known substances miltirone (1), tanshinone II a (2), 1,2 dihydrotanshinquinone (3), methylenetanshinquinone (4), 1-oxomiltirone (5), 11-hydroxymiltiodiol (6), tanshinone I (7), Methyl tanshinonate (8), and cryptotanshinone (9). The IC₅₀s of the compounds were determined against the two parasites and rat myoblast (L6) cells. They ranged from 4.1 µM to over 30 µM against P. falciparum K1 strain with selectivity indices (SI) from 0.3 to 1.9. IC₅₀s against T. brucei rhodesiense STIB 900 were from 0.5 µM (1, 4) to over 30 µM, and 4 showed the greatest selective activity with an SI of 24.|