Methyl trans-cinnamate | CAS:1754-62-7

Methyl trans-cinnamate

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Description:

Methyl trans-cinnamate possesses an antimicrobial ability. Methyl trans-cinnamate can strongly inhibit both monophenolase and diphenolase activity of mushroom tyrosinase.

Targets:

Antifection | Tyrosinase

In vitro:

Journal of Agricultural and Food Chemistry,2009,57(6):2565-9.

Inhibitory Effects of Methyl trans -Cinnamate on Mushroom Tyrosinase and Its Antimicrobial Activities.[Reference: WebLink]

The control of food browning and growth of disease-causing microorganisms is critical to maintaining the quality and safety of food. Tyrosinase is the key enzyme in food browning.
METHODS AND RESULTS:
The inhibitory effect of Methyl trans-cinnamate on the activity of tyrosinase has been investigated. Methyl trans-cinnamate can strongly inhibit both monophenolase and diphenolase activity of mushroom tyrosinase. When the concentration of Methyl trans-cinnamate reached 2.5 mM, the lag time was lengthened from 32 to 160 s and the steady-state activity was lost about 65%. The IC50 value was 1.25 mM. For the diphenolase activity, the inhibition of Methyl trans-cinnamate displayed a reversible and noncompetitive mechanism. The IC50 value was 1.62 mM, and the inhibition constant (K-I) was determined to be 1.60 mM. Moreover, the antibacterial activity against Escherichia coli, Bacillus subtilis and Staphyloccocus aureus and antifungal activity against Candida albicans were tested.
CONCLUSIONS:
The results showed that Methyl trans-cinnamate possessed an antimicrobial ability.

Methyl trans-cinnamate Description

Source:	The essential oils of Zanthoxylum alatum.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Methyl trans-cinnamate
Price:	$30 / 20mg
CAS No.:	1754-62-7
Catalog No.:	CFN70076
Molecular Formula:	C₁₀H₁₀O₂
Molecular Weight:	162.1 g/mol
Purity:	>=98%
Type of Compound:	Phenylpropanoids
Physical Desc.:	Powder
Source:	The essential oils of Zanthoxylum alatum.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS
Similar structural:	Comparison
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Phenylpropanoids Compound Library Tyrosinase Inhibitor Library Antifection Inhibitor Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	6.169 mL	30.8452 mL	61.6903 mL	123.3806 mL	154.2258 mL
5 mM	1.2338 mL	6.169 mL	12.3381 mL	24.6761 mL	30.8452 mL
10 mM	0.6169 mL	3.0845 mL	6.169 mL	12.3381 mL	15.4226 mL
50 mM	0.1234 mL	0.6169 mL	1.2338 mL	2.4676 mL	3.0845 mL
100 mM	0.0617 mL	0.3085 mL	0.6169 mL	1.2338 mL	1.5423 mL

CFN94010	Daturaolone	41498-80-0	440.71	C₃₀H₄₈O₂
CFN60226	Vismodegib (GDC-0449)	879085-55-9	421.3	C₁₉H₁₄Cl₂N₂O₃S
CFN96323	Dihydrosesamin	83708-70-7	356.4	C₂₀H₂₀O₆
CFN97826	3,4'-Dihydroxy-3',5'-dimethoxypropiophenone	136196-47-9	226.23	C₁₁H₁₄O₅