Mogroside II-A1 | CAS:88901-44-4 | Manufacturer ChemFaces

Mogroside II-A1

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Description:

Mogroside II-A1 exhibits inhibitory effects with IC50 values of 346-400 mol ratio/32 pmol TPA. and shows weak inhibitory effects on activation of (+/-)-(E)-methyl-2-[(E)-hydroxyimino]-5-nitro-6-methoxy-3-hexemide (NOR 1), a nitric oxide (NO) donor.

Targets:

In vitro:

J Nat Prod. 2007 May;70(5):783-8.

Cucurbitane glycosides from the fruits of Siraitia gros venorii and their inhibitory effects on Epstein-Barr virus activation.[Pubmed: 17477572 ]

METHODS AND RESULTS:
Six new cucurbitane glycosides, mogroside II B (2), 11-deoxymogroside III (4), 7-oxomogroside II E (5), 7-oxomogroside V (6), 11-oxomogroside II A1 (7), and 11-oxomogroside IV A (8), and two known but new naturally occurring cucurbitane glycosides, Mogroside II-A1 (1) and mogroside-III A2 (3), were isolated from an ethanol extract of the fruits of Siraitia grosvenorii.
CONCLUSIONS:
Upon evaluation of compounds 1-8 for inhibitory effects against the Epstein-Barr virus early antigen (EBV-EA) activation induced by 12-O-tetradecanoylphorbol-13-acetate (TPA), all compounds exhibited inhibitory effects with IC50 values of 346-400 mol ratio/32 pmol TPA. In addition, compounds 1-8 showed weak inhibitory effects on activation of (+/-)-(E)-methyl-2-[(E)-hydroxyimino]-5-nitro-6-methoxy-3-hexemide (NOR 1), a nitric oxide (NO) donor.

Mogroside II-A1 Description

Source:	The fruits of Siraitia grosvenorii Swingle.
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Mogroside II-A1
Price:
CAS No.:	88901-44-4
Catalog No.:	CFN92947
Molecular Formula:	C₄₂H₇₂O₁₄
Molecular Weight:	801.01 g/mol
Purity:	>=98%
Type of Compound:	Triterpenoids
Physical Desc.:	Powder
Source:	The fruits of Siraitia grosvenorii Swingle.
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Download:	COA MSDS
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Triterpenoids Compound Library NO Inhibitor Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	1.2484 mL	6.2421 mL	12.4842 mL	24.9685 mL	31.2106 mL
5 mM	0.2497 mL	1.2484 mL	2.4968 mL	4.9937 mL	6.2421 mL
10 mM	0.1248 mL	0.6242 mL	1.2484 mL	2.4968 mL	3.1211 mL
50 mM	0.025 mL	0.1248 mL	0.2497 mL	0.4994 mL	0.6242 mL
100 mM	0.0125 mL	0.0624 mL	0.1248 mL	0.2497 mL	0.3121 mL

CFN92190	Mogroside III	130567-83-8	963.2	C₄₈H₈₂O₁₉
CFN92192	11-Oxomogroside III	952481-53-7	961.2	C₄₈H₈₀O₁₉
CFN70309	11-Oxomogroside IIIE	2096516-68-4	961.2	C₄₈H₈₀O₁₉
CFN92203	Mogroside II-A2	88901-45-5	801.0	C₄₂H₇₂O₁₄
CFN95305	11-Oxomogroside IIA2	2170761-37-0	799.0	C₄₂H₇₀O₁₄
CFN90389	Mogroside IV	89590-95-4	1125.31	C₅₄H₉₂O₂₄
CFN91126	11-Oxomogroside IV	2096516-32-2	1123.3	C₅₄H₉₀O₂₄
CFN92188	Mogroside IVa	88901-41-1	1125.3	C₅₄H₉₂O₂₄
CFN95607	11-Oxomogroside IVa	952481-54-8	1123.3	C₅₄H₉₀O₂₄
CFN92189	Mogroside IVe	88915-64-4	1125.3	C₅₄H₉₂O₂₄