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    Mulberrofuran A
    Information
    CAS No. 68978-04-1 Price
    Catalog No.CFN92772Purity>=98%
    Molecular Weight392.5Type of CompoundPhenols
    FormulaC25H28O4Physical DescriptionPowder
    Download Manual    COA    MSDSSimilar structuralComparison (Web)
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    Biological Activity
    Description: 1. Mulberrofuran A can inhibit the formations of 12-hydroxy-, 8, 10-heptadecatrienoic acid (HHT) and thromboxane B2, but it can increase the formation of 12-hydroxy-5, 8, 10, 14-eicosatetraenoic acid (12-HETE).
    Targets: COX
    Mulberrofuran A Description
    Source: The root bark of Morus alba L.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.

    PMID: 29328914

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.

    PMID: 29149595

    Scientific Reports 2017 Dec 11;7(1):17332.
    doi: 10.1038/s41598-017-17427-6.

    PMID: 29230013

    Molecules. 2017 Oct 27;22(11). pii: E1829.
    doi: 10.3390/molecules22111829.

    PMID: 29077044

    J Cell Biochem. 2018 Feb;119(2):2231-2239.
    doi: 10.1002/jcb.26385.

    PMID: 28857247

    Phytomedicine. 2018 Feb 1;40:37-47.
    doi: 10.1016/j.phymed.2017.12.030.

    PMID: 29496173
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.5478 mL 12.7389 mL 25.4777 mL 50.9554 mL 63.6943 mL
    5 mM 0.5096 mL 2.5478 mL 5.0955 mL 10.1911 mL 12.7389 mL
    10 mM 0.2548 mL 1.2739 mL 2.5478 mL 5.0955 mL 6.3694 mL
    50 mM 0.051 mL 0.2548 mL 0.5096 mL 1.0191 mL 1.2739 mL
    100 mM 0.0255 mL 0.1274 mL 0.2548 mL 0.5096 mL 0.6369 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Mulberrofuran A References Information
    Citation [1]

    Chem. Pharm. Bull., 1986, 34(3):1223-7

    Effects of flavonoids and related compounds from mulberry tree on arachidonate metabolism in rat platelet homogenates[Pubmed: 3089631]
    The effects of various flavonoids and related compounds isolated from the root bark of mulberry tree on rat platelet lipoxygenase and cyclooxygenase products formed from [1-14C] arachidonic acid were studied. Morusin was found to inhibit the formations of 12-hydroxy-, 8, 10-heptadecatrienoic acid (HHT) and thromboxane B2 (cyclooxygenase products) more strongly than the formation of 12-hydroxy-5, 8, 10, 14-eicosatetraenoic acid (12-HETE) (12-lipoxygenase product). Oxydihydromorusin and kuwanon C were also found to inhibit the formation of thromboxane B2 more strongly than the formations of HHT and 12-HETE. Mulberrofuran A inhibited the formations of HHT and thromboxane B2, but it increased the formation of 12-HETE. Albanol B and mulberrofuran F did not affect arachidonate metabolism in rat platelet homogenates.