Science | Nature | Cell | View More
Natural Products
N-trans-caffeoyltyramine
N-trans-caffeoyltyramine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name N-trans-caffeoyltyramine
Price: $318 / 5mg
CAS No.: 103188-48-3
Catalog No.: CFN95265
Molecular Formula: C17H17NO4
Molecular Weight: 299.3 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The roots of Litsea hypophaea
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $222.6 / In-stock
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • Center for protein Engineering ... (Belgium)
  • University of Liège (Belgium)
  • University of Queensland (Australia)
  • University of Helsinki (Finland)
  • Almansora University (Egypt)
  • Universidade do Porto (Portugal)
  • Subang Jaya Medical Centre (Malaysia)
  • Calcutta University (India)
  • University of Hawaii Cancer Center (USA)
  • University of Wollongong (Australia)
  • University of East Anglia (United Kingdom)
  • More...
Package
Featured Products
Monomethyl lithospermate

Catalog No: CFN91005
CAS No: 933054-33-2
Price: $333/10mg
20-O-Glucoginsenoside Rf

Catalog No: CFN95036
CAS No: 68406-27-9
Price: $318/5mg
Isorhyncophylline

Catalog No: CFN92553
CAS No: 6859-01-4
Price: $158/20mg
Chebulanin

Catalog No: CFN92294
CAS No: 166833-80-3
Price: $ / mg
Paeonol

Catalog No: CFN98926
CAS No: 552-41-0
Price: $30/20mg
Gypenoside XVII

Catalog No: CFN90193
CAS No: 80321-69-3
Price: $80/20mg
4-Methoxyglucobrassicin

Catalog No: CFN00505
CAS No: 83327-21-3
Price: $ / mg
Isochlorogenic acid C

Catalog No: CFN99120
CAS No: 32451-88-0
Price: $70/20mg
Stigmasterol glucoside

Catalog No: CFN98000
CAS No: 19716-26-8
Price: $368/5mg
Estragole

Catalog No: CFN70065
CAS No: 140-67-0
Price: $30/20mg
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: N-trans-caffeoyltyramine is a novel and potent modulator of inflammatory responses.
In vitro:
International Journal of Molecular Medicine, 2015,3:1042-1048.
N‑trans‑ρ‑caffeoyl tyramine isolated from Tribulus terrestris exerts anti‑inflammatory effects in lipopolysaccharide‑stimulated RAW 264.7 cells.[Reference: WebLink]
Inflammation is induced by the expression of cyclooxygenase‑2 (COX‑2), which is an important mediator of chronic inflammatory diseases, such as rheumatoid arthritis, asthma and inflammatory bowel disease. Tribulus terrestris (T. terrestris) is known to have a beneficial effect on inflammatory diseases.
METHODS AND RESULTS:
In this study, we investigated the effects of N‑trans‑ρ‑caffeoyltyramine (N-trans-caffeoyltyramine,CT) isolated from T. terrestris on the production of nitric oxide (NO), and the expression of pro‑inflammatory cytokines and COX‑2 in lipopolysaccharide (LPS)‑stimulated RAW 264.7 cells. We also aimed to elucidate the molecular mechanisms involved. We found that the ethanolic extract of T. terrestris (EETT) and CT inhibited the production of NO, tumor necrosis factor‑α (TNF‑α), interleukin (IL)‑6 and IL‑10 in the LPS‑stimulated RAW 264.7 cells in a dose‑dependent manner. They were determined by reverse transcription-polymerase chain reaction (RT-PCR) and enzyme-linked immunosorbent assay (ELISA). In addition, CT markedly suppressed the expression of COX‑2 and the production of prostaglandin E2 (PGE2) in response to LPS stimulation. Furthermore, CT markedly decreased p‑c‑Jun N‑terminal kinase (p‑JNK) protein expression in LPS‑stimulated RAW 264.7 cells. COX-2 and p-JNK were measured by western blot analysis.
CONCLUSIONS:
Taken together, these findings indicate that CT isolated from T. terrestris is a novel and potent modulator of inflammatory responses. Thus, it may prove benefiical to further evaluate CT as a possible treatment for chronic inflammatory diseases.
N-trans-caffeoyltyramine Description
Source: The roots of Litsea hypophaea
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
(-)-Cadin-4,10(15)-dien-11-oic aci...

Catalog No: CFN95246
CAS No: 1124353-23-6
Price: $318/5mg
Maculosidin

Catalog No: CFN95126
CAS No: 522-19-0
Price: $413/5mg
Lucidumol A

Catalog No: CFN95059
CAS No: 217476-73-8
Price: $318/5mg
Oxyphyllol B

Catalog No: CFN95575
CAS No: 226546-99-2
Price: $/mg
Cajanine

Catalog No: CFN95448
CAS No: 87402-84-4
Price: $318/5mg
Astin C

Catalog No: CFN95189
CAS No: 148057-23-2
Price: $318/10mg
1-Phenylethyl beta-D-glucoside

Catalog No: CFN95574
CAS No: 93199-03-2
Price: $318/5mg
2',4'-Dihydroxychalcone

Catalog No: CFN95493
CAS No: 1776-30-3
Price: $318/20mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.3411 mL 16.7056 mL 33.4113 mL 66.8226 mL 83.5282 mL
5 mM 0.6682 mL 3.3411 mL 6.6823 mL 13.3645 mL 16.7056 mL
10 mM 0.3341 mL 1.6706 mL 3.3411 mL 6.6823 mL 8.3528 mL
50 mM 0.0668 mL 0.3341 mL 0.6682 mL 1.3365 mL 1.6706 mL
100 mM 0.0334 mL 0.1671 mL 0.3341 mL 0.6682 mL 0.8353 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Journal of the Chinese Chemical Society, 2013, 44(3):313-319.
The Constituents from the Stems of Annona cherimola.[Reference: WebLink]

METHODS AND RESULTS:
Thirty‐five compounds including twenty‐one alkaloids, lysicamine (1 ), liriodenine (2 ), atherospermidine (3 ), oxoxylopine (4 ), oxoanolobine (5 ), oxoglaucine (6 ), (‐)‐anonaine (7 ), (‐)‐asimilobine (8 ), (‐)‐xylopine (9 ), (‐)‐anolobine (10 ), (‐)‐norisocorydine (11 ), (+)‐laurotetanine (12 ), (+)‐isocorydine (13 ), (‐)‐N‐methylasimilobine (14 ), (+)‐N‐methyllaurotetanine (15 ), (‐)‐norushinsunine (16 ), (‐)‐ushinsunine (17 ), (‐)‐N‐formylanonaine (18 ), (+)‐stepharine (19 ), (+)‐orentaline (20 ), and (‐)‐kikemanine (21 ); four kauranes, ent‐kaur‐16‐en‐19‐oic acid (22 ), 16β‐hydroxy‐17‐acetoxy‐ent‐kauran‐19‐al (23 ), 17‐acetoxy‐16β‐ent‐kauran‐19‐oic acid (24 ), and 16β‐hydroxy‐17‐acetoxy‐ent‐kauran‐19‐oic acid (25 ); two amides, N‐trans‐femloyltyramine (26 ), and N-trans-caffeoyltyramine (27 ); one purine, adenosine (28 ); one lactam amide, squamolone (29 ); and six steroids, β‐sitosterol (30 ), stigmasterol (31 ), β‐sitostenone (32 ), stigmasta‐4,22‐dien‐3‐one (33 ), 6β‐hydroxy‐β‐sitosterone (34 ), and 6β‐hydroxystigmasterone (35 ) are isolated from the stems of Annona cherimola.
CONCLUSIONS:
These compounds were characterized and identified by physical and spectral evidence. Among them, (‐)‐norisocorydine (11) was elucidated as a new enantiomer with a levorotary configuration, which is isolated for the first time.
Monomethyl lithospermate

Catalog No: CFN91005
CAS No: 933054-33-2
Price: $333/10mg
20-O-Glucoginsenoside Rf

Catalog No: CFN95036
CAS No: 68406-27-9
Price: $318/5mg
Isorhyncophylline

Catalog No: CFN92553
CAS No: 6859-01-4
Price: $158/20mg
Chebulanin

Catalog No: CFN92294
CAS No: 166833-80-3
Price: $ / mg
Paeonol

Catalog No: CFN98926
CAS No: 552-41-0
Price: $30/20mg
Gypenoside XVII

Catalog No: CFN90193
CAS No: 80321-69-3
Price: $80/20mg
4-Methoxyglucobrassicin

Catalog No: CFN00505
CAS No: 83327-21-3
Price: $ / mg
Isochlorogenic acid C

Catalog No: CFN99120
CAS No: 32451-88-0
Price: $70/20mg
Stigmasterol glucoside

Catalog No: CFN98000
CAS No: 19716-26-8
Price: $368/5mg
Estragole

Catalog No: CFN70065
CAS No: 140-67-0
Price: $30/20mg
Tags: buy N-trans-caffeoyltyramine | N-trans-caffeoyltyramine supplier | purchase N-trans-caffeoyltyramine | N-trans-caffeoyltyramine cost | N-trans-caffeoyltyramine manufacturer | order N-trans-caffeoyltyramine | N-trans-caffeoyltyramine distributor