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    (Z)-23-Coumaroylhederagenin
    (Z)-23-Coumaroylhederagenin
    Information
    CAS No. 654678-61-2 Price
    Catalog No.CFN92845Purity>=98%
    Molecular Weight618.4Type of CompoundTriterpenoids
    FormulaC39H54O6Physical DescriptionPowder
    Download     COA    MSDS    SDFSimilar structuralComparison (Web)
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    (Z)-23-Coumaroylhederagenin Description
    Source: The herbs of Ludwigia octovalvis
    Biological Activity or Inhibitors: 1. (Z)-23-Coumaroylhederagenin shows significant cytotoxicity against two human tumor cell lines, namely, oral epidermoid carcinoma KB and colorectal carcinoma HT29, and the IC(50) value in the range 1.2-3.6 microM.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.

    PMID: 29328914

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
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    Scientific Reports 2017 Dec 11;7(1):17332.
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    PMID: 29230013

    Molecules. 2017 Oct 27;22(11). pii: E1829.
    doi: 10.3390/molecules22111829.

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    J Cell Biochem. 2018 Feb;119(2):2231-2239.
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    Phytomedicine. 2018 Feb 1;40:37-47.
    doi:10.1016/j.phymed.2017.12.030

    PMID: 29496173
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.6171 mL 8.0854 mL 16.1708 mL 32.3415 mL 40.4269 mL
    5 mM 0.3234 mL 1.6171 mL 3.2342 mL 6.4683 mL 8.0854 mL
    10 mM 0.1617 mL 0.8085 mL 1.6171 mL 3.2342 mL 4.0427 mL
    50 mM 0.0323 mL 0.1617 mL 0.3234 mL 0.6468 mL 0.8085 mL
    100 mM 0.0162 mL 0.0809 mL 0.1617 mL 0.3234 mL 0.4043 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    (Z)-23-Coumaroylhederagenin References Information
    Citation [1]

    J Nat Prod. 2004 Jan;67(1):91-3.

    Three new oleanane-type triterpenes from Ludwigia octovalvis with cytotoxic activity against two human cancer cell lines.[Pubmed: 14738395 ]
    Three new oleanane-type triterpenes, (23Z)-coumaroylhederagenin ((Z)-23-Coumaroylhederagenin,1), (23E)-coumaroylhederagenin (2), and (3Z)-coumaroylhederagenin (3), together with two known triterpene acids, oleanolic acid and ursolic acid, have been isolated from the whole plant of Ludwigia octovalvis, and their structures have been elucidated by spectroscopic methods. All three new triterpenes showed significant cytotoxicity against two human tumor cell lines, namely, oral epidermoid carcinoma KB and colorectal carcinoma HT29, and gave IC(50) values in the range 1.2-3.6 microM.