ChemFaces is a professional high-purity natural products manufacturer.
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1. Reference standards
2. Pharmacological research
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More articles cited ChemFaces products.
Proc Natl Acad Sci U S A. 2016 Jul 26;Free Radic Biol Med.2017 Nov;Sci Rep. 2017 Oct 11;Fitoterapia. 2018 Jan;Gorana Nedin Rankovi?2017 Jan 15
Front Pharmacol. 2016 Nov 30Oncol Rep.2015 Dec 22. Integr Med Res.2017 Dec;Mol. & Cell. ToxicologySep. 2017;University of Limpopo2016
Phytomedicine.2018 Jan 1;Journal of Functional FoodsFeb. 2018;Phytomedicine1 Feb. 2018;Acta Physiologiae PlantarumJanuary 2016, 38:7
Our products had been exported to the following research institutions and universities, And still growing.
National Cancer Center Research ... (Japan)Heinrich-Heine-University Düsse... (Germany)University of Sao Paulo (Brazil)Shanghai Institute of Biochemist... (China)
Universidade Federal de Pernambu... (Brazil)Universidade Federal de Santa Ca... (Brazil)Complutense University of Madrid (Spain)Cornell University (USA)
S.N.D.T. Women's University (India)Johannes Gutenberg University Ma... (Germany)Monash University Malaysia (Malaysia)
|| 1. Oleacein is a strong Angiotensin Converting Enzyme (ACE)-inhibitor (IC50 = 26 uM).|
||The herbs of Lepidium sativum
||DMSO, Pyridine, Methanol, Ethanol, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.PMID: 29328914
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.PMID: 29149595
Scientific Reports 2017 Dec 11;7(1):17332.doi: 10.1038/s41598-017-17427-6.PMID: 29230013
Molecules. 2017 Oct 27;22(11). pii: E1829.doi: 10.3390/molecules22111829.PMID: 29077044
J Cell Biochem. 2018 Feb;119(2):2231-2239.doi: 10.1002/jcb.26385. PMID: 28857247
Phytomedicine. 2018 Feb 1;40:37-47. doi: 10.1016/j.phymed.2017.12.030.PMID: 29496173
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Oleoside References Information
Phytomedicine, 1996, 2(4):319-25.
|Isolation of an angiotensin converting enzyme (ACE) inhibitor from Olea europaea and Olea lancea.[Pubmed: 23194770 ]|
|The aqueous extract of the leaves of Olea europaea and Olea lancea both inhibited Angiotensin Converting Enzyme (ACE) in vitro. A bioassay-directed fractionation resulted in the isolation of a strong ACE-inhibitor namely the secoiridoid 2-(3,4-dihydroxyphenyl)ethyl 4-formyl-3-(2-oxoethyl)-4 E-hexenoate (oleacein) (IC(50) = 26 μM). Five secoiridoid glycosides (oleuropein, ligstroside, excelcioside, Oleoside 11-methyl ester, Oleoside) isolated from Oleaceous plants showed no significant ACE-inhibition whereas, after enzymatic hydrolysis, the ACE-inhibition at 0.33 mg/ml was between 64% to 95%. Secoiridoids have not been described previously in the literature as inhibitors of ACE. Oleacein showed a low toxicity in the brine shrimp (Artemia satina) lethality test (LC(50) (24 h) = 969 ppm).