Panaxyne | CAS:122855-49-6 | Manufacturer ChemFaces

Panaxyne

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Description:

Panaxyne shows significant and selective cytotoxicity against SK-OV-3 with ED50 value of 1.40 microM.

In vitro:

Arch Pharm Res. 2008 Feb;31(2):154-9.

Polyacetylenes from the roots of cultivated-wild ginseng and their cytotoxicity in vitro.[Pubmed: 18365683]

Column chromatographic separation of the roots of cultivated-wild ginseng (Jangnoisam) led to the isolation of seven polyacetylenes (1-7).
METHODS AND RESULTS:
Their structures were determined by spectroscopic methods to be panaxynol (1), ginsenoyne-A (2), panaxydol (3), 10-methoxy heptadeca-1-ene-4, 6-dyne-3, 9-diol (4) (3R, 9R, 10R)-panaxytriol (5), Panaxyne (6), and ginsenoyne-C (7). These compounds were isolated from this source for the first time. The compounds were tested for their cytotoxic activity against four human cancer cell lines (A549, SK-OV-3, SK-MEL-2, and HCT-15) in vitro using the SRB method.
CONCLUSIONS:
Panaxydol (3) and Panaxyne (6) showed significant and selective cytotoxicity against SK-OV-3 with ED50 values 2.93 and 1.40 microM, respectively.

Panaxyne Description

Source:	The roots of Panax ginseng
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Panaxyne
Price:
CAS No.:	122855-49-6
Catalog No.:	CFN96202
Molecular Formula:	C₁₄H₂₀O₂
Molecular Weight:	220.3 g/mol
Purity:	>=98%
Type of Compound:	Lipids
Physical Desc.:	Powder
Source:	The roots of Panax ginseng
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Cytotoxic Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	4.5393 mL	22.6963 mL	45.3926 mL	90.7853 mL	113.4816 mL
5 mM	0.9079 mL	4.5393 mL	9.0785 mL	18.1571 mL	22.6963 mL
10 mM	0.4539 mL	2.2696 mL	4.5393 mL	9.0785 mL	11.3482 mL
50 mM	0.0908 mL	0.4539 mL	0.9079 mL	1.8157 mL	2.2696 mL
100 mM	0.0454 mL	0.227 mL	0.4539 mL	0.9079 mL	1.1348 mL

CFN95665	Panaxytriol	87005-03-6	278.4	C₁₇H₂₆O₃
CFN96202	Panaxyne	122855-49-6	220.3	C₁₄H₂₀O₂
CFN97743	8-Acetoxypentadeca-1,9Z-diene-4,6-diyn-3-ol	41682-30-8	274.36	C₁₇H₂₂O₃
CFN98061	9,17-Octadecadiene-12,14-diyne-1,11,16-triol	211238-60-7	290.4	C₁₈H₂₆O₃
CFN98068	1-Acetoxy-9,17-octadecadiene-12,14-diyne-11,16-diol	213905-35-2	332.4	C₂₀H₂₈O₄
CFN93212	Panaxynol	81203-57-8	244.4	C₁₇H₂₄O
CFN98220	Falcarindiol	225110-25-8	260.4	C₁₇H₂₄O₂
CFN96027	Falcarinol	21852-80-2	244.4	C₁₇H₂₄O
CFN96044	Ginsenoyne K	141947-42-4	276.4	C₁₇H₂₄O₃
CFN92356	Lobetyol	136171-87-4	234.3	C₁₄H₁₈O₃