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Pelirine
Pelirine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Pelirine
Price:
CAS No.: 30435-26-8
Catalog No.: CFN96181
Molecular Formula: C21H26N2O3
Molecular Weight: 354.5 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The roots of Rauvolfia verticillata
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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  • Universidade de Franca (Brazil)
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  • Chiang Mai University (Thailand)
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Pelirine is a natural product from Rauvolfia verticillata.
Pelirine Description
Source: The roots of Rauvolfia verticillata
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
More...

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.8209 mL 14.1044 mL 28.2087 mL 56.4175 mL 70.5219 mL
5 mM 0.5642 mL 2.8209 mL 5.6417 mL 11.2835 mL 14.1044 mL
10 mM 0.2821 mL 1.4104 mL 2.8209 mL 5.6417 mL 7.0522 mL
50 mM 0.0564 mL 0.2821 mL 0.5642 mL 1.1283 mL 1.4104 mL
100 mM 0.0282 mL 0.141 mL 0.2821 mL 0.5642 mL 0.7052 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Planta Medica, 1976 , 29 (03) :201-207.
Alkaloids of Rauwolfia cambodiana from Thailand.[Reference: WebLink]

METHODS AND RESULTS:
The roots of Rauwolfia cambodiana yielded the indole alkaloids ajmaline, aricine, isoreserpiline, Pelirine, reserpiline and reserpine. The principal alkaloid was isoreserpiline. The alkaloid pattern differed from that of R. verticillata but was similar to the alkaloid pattern of R. perakensis, a species with which R. cambodiana may be synonymous.
CONCLUSIONS:
The occurrence of alkaloids in the six S. E. Asian Rauwolfia species could not be related to Pichon's classification of the genus.
CFN97884Vellosimine6874-98-2292.4C19H20N2O
CFN92612(+)-Affinisine2912-11-0308.4C20H24N2O
CFN96211Macusine B6792-07-0309.4C20H25N2O
CFN96170Spegatrine47326-53-4325.4C20H25N2O2
CFN9609710-Hydroxy-16-epiaffinine82513-70-0340.4C20H24N2O3
CFN96181Pelirine30435-26-8354.5C21H26N2O3
CFN96148Taberpsychine19452-84-7308.4C20H24N2O
CFN97989N-Methoxyanhydrovobasinediol125180-42-9338.5C21H26N2O2
CFN9603016-Epivoacarpine114027-38-2368.4C21H24N2O4
CFN96018Gelsempervine A865187-17-3382.5C22H26N2O4
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