|Source:||The herbs of Catharanthus roseus G. Don|
|Biological Activity or Inhibitors:||1. Perivine might resolve the instability of the RbAp48-FOG1 complex and thus be used in Alzheimer's disease therapy.
|Solvent:||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.|
|Storage:||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
|After receiving:||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.|
|1 mg||5 mg||10 mg||20 mg||25 mg|
|1 mM||2.9551 mL||14.7754 mL||29.5508 mL||59.1017 mL||73.8771 mL|
|5 mM||0.591 mL||2.9551 mL||5.9102 mL||11.8203 mL||14.7754 mL|
|10 mM||0.2955 mL||1.4775 mL||2.9551 mL||5.9102 mL||7.3877 mL|
|50 mM||0.0591 mL||0.2955 mL||0.591 mL||1.182 mL||1.4775 mL|
|100 mM||0.0296 mL||0.1478 mL||0.2955 mL||0.591 mL||0.7388 mL|
Biomed Res Int. 2014;2014:764946.
|Lead discovery for Alzheimer's disease related target protein RbAp48 from traditional Chinese medicine.[Pubmed: 25165715]|
|The protein structure does not affect ligand binding, and the top three TCM candidates Bittersweet alkaloid II, Eicosandioic acid, and Perivine might resolve the instability of the RbAp48-FOG1 complex and thus be used in Alzheimer's disease therapy.|