ChemFaces is a professional high-purity natural products manufacturer.
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1. Reference standards
2. Pharmacological research
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More articles cited ChemFaces products.
Phytomedicine2015 August 14Acta ChromatographicaOct. 11, 2016J Sci Food Agric. 2017 Jul 22. Oncotarget. 2016 Aug 19Mol Cells.2015 Sep 30;38(9):765-72.
Sci Rep. 2017 Jun 12;Front Pharmacol. 2017 Apr 25;J. Acta Agr. Scandinavica17 Apr 2017The Japan Society for Analy. Chem.2017 Nov. 8;Front Plant Sci. 2017 May 8;
Journal of Agricultural Science2015 Sep 15Sci Rep. 2017 Dec 11;Mol Med Rep.2014 May;9(5):1653-9.Tropical J. of Pha. ResearchNo 3 (2017)
Our products had been exported to the following research institutions and universities, And still growing.
University of Medicine and Pharm... (Romania)University of Minnesota (USA)Mahatma Gandhi University (India)University of Wisconsin-Madison (USA)
Charles Sturt University (Denmark)Kitasato University (Japan)University of Eastern Finland (Finland)University of Ioannina (Greece)
Max-Planck-Insitut (Germany)Lodz University of Technology (Poland)VIB Department of Plant Systems ... (Belgium)
||Picfeltarraenin X shows stronger AChE inhibition than the known AChE inhibitor Tacrine. |
Picfeltarraenin X Description
||The herbs of Picria felterrae Lour.
||DMSO, Pyridine, Methanol, Ethanol, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.PMID: 29328914
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.PMID: 29149595
Scientific Reports 2017 Dec 11;7(1):17332.doi: 10.1038/s41598-017-17427-6.PMID: 29230013
Molecules. 2017 Oct 27;22(11). pii: E1829.doi: 10.3390/molecules22111829.PMID: 29077044
J Cell Biochem. 2018 Feb;119(2):2231-2239.doi: 10.1002/jcb.26385. PMID: 28857247
Phytomedicine. 2018 Feb 1;40:37-47. doi:10.1016/j.phymed.2017.12.030PMID: 29496173
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
|J Asian Nat Prod Res. 2006 Sep;8(6):491-4. |
|Two new triterpenoids from Picria fel-terrae.[Pubmed: 16931422]|
METHODS AND RESULTS:
Two new triterpenoids, picfeltarraegenin VII (1) and Picfeltarraenin X (2), have been isolated from Picria fel-terrae Lour., along with three known ones, picfeltarraegenin VI (3), picfeltarraenins VI (4) and VII (5).
Their structures have been elucidated by means of spectroscopic methods.
|Pharmacogn Mag. 2013 Oct;9(Suppl 1):S25-31. |
|Bioassay- and liquid chromatography/mass spectrometry-guided acetylcholinesterase inhibitors from Picriafel-terrae.[Pubmed: 24143041]|
|Picria fel-terrae is a traditional Chinese medicine.
METHODS AND RESULTS:
A new approach to the search for acetylcholinesterase (AChE) inhibitors from Picria fel-terrae is presented.
Bioassay- and LC-MS-guided fractionation of the ethyl acetate extract was from traditional Chinese medicine P.fel-terrae. Following primary extraction, the ethyl acetate extracts fraction of P.fel-terrae showed strong AChE inhibitory activities. So the sample was separated using highperformance liquid chromatography (HPLC). The effluent was split towards two identical 96-well fraction collectors, and the presence of the biologically interesting portion and chromatographic fractions could be readily detected by analyzing selected ion chromatograms through an electrophoresis-electrospray ionization mass spectrometry (ESIMS) system for accurate mass measurement. One 96-well plate was used for a bioassay (AChE-inhibitory assay) and detected the bioactivity and position of the relevant peak in the chromatogram. The positive well in the second 96-well plate was used for identification by LC-(+) ESIMS.
As abovementioned, the AChE inhibitory constituents from P.fel-terrae by LC-bioassay-ESIMS were rapid identified. Liquid chromatography/ mass spectrometry (LC-MS) screening detected the presence of six active compounds, identified as picfeltarraenin IA (1), picfeltarraenin IB (2), picfeltarraenin IV (3), Picfeltarraenin X (4), Picfeltarraenin XI (5), and one unknown compound. The structures were further determined by 13C NMR. The six compounds expressed stronger AChE inhibition than the known AChE inhibitorTacrine. Above all, the value of this LC-bioassay-ESIMS methodology is highlighted by the finding and structure elucidation of the active constituents from many other structural families of natural products.