ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
More articles cited ChemFaces products.
Org Biomol Chem. 2017 Jul 25.J Ethnopharmacol.23 February 2017Advance Publication2015 Aug 18Int. J. of Food Properties08 Feb 2017;BangaloreOct/Dec 2017;
Biofactors.2017 Oct 24.J Ethnopharmacol. 2017 Jan 20;ScientificWorldJournal. 2014 Feb 9.Phytomedicine1 March 2018;Hum Exp Toxicol. 2016 Dec 9.
J. Acta Agr. Scandinavica17 Apr 2017J Pharm Biomed Anal. 2017 Jun 5;Int J Mol Sci.2015 Jan 6;16(1):1232-51.BMC Complement Altern Med.2016 Jul 13
Our products had been exported to the following research institutions and universities, And still growing.
Sri Ramachandra University (India)Center for protein Engineering (... (Belgium)Universidade Federal de Goias (U... (Brazil)Colorado State University (USA)
University of Fribourg (Switzerland)The Australian National University (Australia)Funda??o Universitária de Desen... (Brazil)National Research Council of Can... (Canada)
Universidade Federal de Pernambu... (Brazil)Stanford University (USA)Universitas Airlangga (Indonesia)
|| Piperlotine D shows potent antiplatelet aggregation activity. |
|J Agric Food Chem. 2007 Nov 14;55(23):9436-42. |
|Isolation and identification of antiplatelet aggregatory principles from the leaves of Piper lolot.[Pubmed: 17941696]|
METHODS AND RESULTS:
The methanolic extract of Piper lolot, having shown potent inhibitory activity on platelet aggregation induced by arachidonic acid (AA) and platelet activating factor (PAF), was subjected to activity-guided isolation to yield twelve new amide alkaloids, piperlotine A-L (1-12), along with twenty-nine known compounds. Their structures were elucidated on the basis of spectroscopic analysis. The isolated compounds were tested for their inhibitory activity on the rabbit platelet aggregation.
The compounds piperlotine A (1), piperlotine C (3), Piperlotine D (4), piperlotine E (5), 3-phenyl-1-(2,4,6-trihydroxyphenyl)propan-1-one (21), 3-(4-methoxyphenyl)-1-(2,4,6-trihydroxyphenyl)propan-1-one (22), 1-trans-cinnamoylpyrrolidine (24), sarmentine (26), pellitorine (27), methyl 3-phenylpropionate (32), and (10S)-10-hydroxypheophorbide a methyl ester (40) showed potent antiplatelet aggregation activity.
Piperlotine D Description
||The herbs of Piper nigrum L.
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.PMID: 29328914
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.PMID: 29149595
Scientific Reports 2017 Dec 11;7(1):17332.doi: 10.1038/s41598-017-17427-6.PMID: 29230013
Molecules. 2017 Oct 27;22(11). pii: E1829.doi: 10.3390/molecules22111829.PMID: 29077044
J Cell Biochem. 2018 Feb;119(2):2231-2239.doi: 10.1002/jcb.26385. PMID: 28857247
Phytomedicine. 2018 Feb 1;40:37-47. doi:10.1016/j.phymed.2017.12.030PMID: 29496173
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.