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Pterosin Z
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Product Name Pterosin Z
Price:
CAS No.: 34169-69-2
Catalog No.: CFN98442
Molecular Formula: C15H20O2
Molecular Weight: 232.3 g/mol
Purity: >=98%
Type of Compound: Sesquiterpenoids
Physical Desc.: Powder
Source: The rhizomes of Cibotium barometz (L.) J.Sm.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Pterosin Z has smooth muscle relaxant activity, is approximately equipotent with that of the related fungal pterosin (EC50 of 2.9 +/- 1.6 x 10(-6) M).
Targets: Calcium Channel
In vitro:
Planta Med. 1999 Apr;65(3):271-2.
Smooth muscle relaxant activity of pterosin Z and related compounds.[Pubmed: 10232079]

METHODS AND RESULTS:
The natural products Pterosin Z, acetylPterosin Z, originally from the fern Pteridium aquilinum, and their isopterosin analogues have been synthesized and their smooth muscle relaxation activity has been measured. All of the test compounds show activity with Pterosin Z being the most active (EC50 = 1.3 +/- 0.1 x 10(-6) M), exhibiting 100 times the activity reported for the related fern metabolites onitin (EC50 = 1 x 10(-4) M), onotisin (EC50 = 2 x 10(-3) M) and otninoside (EC50 = 7 x 10(-4) M). The smooth muscle relaxant activity of Pterosin Z is approximately equipotent with that of the related fungal pterosin (EC50 of 2.9 +/- 1.6 x 10(-6) M).
CONCLUSIONS:
These results suggest that smooth muscle relaxant activity is reduced when a phenol group is present in the pterosin nucleus and when one of the dimethyl groups is derivatized.
Pterosin Z Description
Source: The rhizomes of Cibotium barometz (L.) J.Sm.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.3048 mL 21.5239 mL 43.0478 mL 86.0956 mL 107.6195 mL
5 mM 0.861 mL 4.3048 mL 8.6096 mL 17.2191 mL 21.5239 mL
10 mM 0.4305 mL 2.1524 mL 4.3048 mL 8.6096 mL 10.7619 mL
50 mM 0.0861 mL 0.4305 mL 0.861 mL 1.7219 mL 2.1524 mL
100 mM 0.043 mL 0.2152 mL 0.4305 mL 0.861 mL 1.0762 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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Price: $30/20mg
Sauchinone

Catalog No: CFN90153
CAS No: 177931-17-8
Price: $60/20mg
Chebulagic acid

Catalog No: CFN92295
CAS No: 23094-71-5
Price: $ / mg
Pinocembrin chalcone

Catalog No: CFN96919
CAS No: 4197-97-1
Price: $/mg
Intermedine N-oxide

Catalog No: CFN00459
CAS No: 95462-14-9
Price: $ / mg
Luteolin-7-O-glucuronide

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Price: $118/20mg
Scopolamine

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Stylopine

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Price: $ / mg
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