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    Randaiol
    Randaiol
    Information
    CAS No. 87562-14-9 Price $333 / 5mg
    Catalog No.CFN96098Purity>=98%
    Molecular Weight242.3Type of CompoundLignans
    FormulaC15H14O3Physical DescriptionPowder
    Download     COA    MSDS    SDFSimilar structuralComparison (Web)
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    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    Our products had been exported to the following research institutions and universities, And still growing.
  • Chang Gung University (Taiwan)
  • Uniwersytet Gdański (Poland)
  • Imperial College London (United Kingdom)
  • Medical University of South Caro... (USA)
  • Research Unit Molecular Epigenet... (Germany)
  • Shanghai University of TCM (China)
  • National Cancer Center Research ... (Japan)
  • MTT Agrifood Research Finland (Finland)
  • Regional Crop Research Institute (Korea)
  • Melbourne University (Australia)
  • Florida International University (USA)
  • More...
  • Package
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    Randaiol Description
    Source: The barks of Magnolia hypoleuca
    Biological Activity or Inhibitors:
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.

    PMID: 29328914

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.

    PMID: 29149595

    Scientific Reports 2017 Dec 11;7(1):17332.
    doi: 10.1038/s41598-017-17427-6.

    PMID: 29230013

    Molecules. 2017 Oct 27;22(11). pii: E1829.
    doi: 10.3390/molecules22111829.

    PMID: 29077044

    J Cell Biochem. 2018 Feb;119(2):2231-2239.
    doi: 10.1002/jcb.26385.

    PMID: 28857247

    Phytomedicine. 2018 Feb 1;40:37-47.
    doi:10.1016/j.phymed.2017.12.030

    PMID: 29496173
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 4.1271 mL 20.6356 mL 41.2712 mL 82.5423 mL 103.1779 mL
    5 mM 0.8254 mL 4.1271 mL 8.2542 mL 16.5085 mL 20.6356 mL
    10 mM 0.4127 mL 2.0636 mL 4.1271 mL 8.2542 mL 10.3178 mL
    50 mM 0.0825 mL 0.4127 mL 0.8254 mL 1.6508 mL 2.0636 mL
    100 mM 0.0413 mL 0.2064 mL 0.4127 mL 0.8254 mL 1.0318 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Randaiol References Information
    Citation [1]

    Phytochemistry.1983;22(2):616–617.

    Biphenyls from the heartwood of taiwan sassafras.[Reference: WebLink]
    Two new biphenyls, randainal and Randaiol, have been isolated from the heartwood of Taiwan sassafras in addition to the known biphenyl magnolol which was found previously in the bark of Magnolia species. The two biphenyls were shown to be 2,2′-dihydroxy-5-allylbiphenyl-5′-propenal and 2,2′,5′-trihydroxy-5-allylbiphenyl on the basis of chemical and spectroscopic evidence.
    Citation [2]

    Planta Medica, 2011 , 77 (12):42.

    New biphenyl derivatives and anti-inflammatory constituents from the stem bark of Magnolia officinalis[Reference: WebLink]
    The stem bark of Magnolia officinalis Rehd. et Wils. (Magnoliaceae) has been used as a traditional medicine for the treatment of gastrointestinal disorders, bronchitis, and emphysema, in China, Taiwan, Japan, and Korea [1]. Chemical studies have revealed a variety of neo-lignans and alkaloids as constituents of this plant. Many of these compounds exhibit central depressant effect, muscle relaxation, and antigastric ulcer, antibacterial, antiallergic, vasorelaxant, and neurotrophic activities. Investigation on EtOAc-soluble fraction of the stem bark of M. officinalis has led to the isolation of three new biphenyls, 5-allyl-5'-(1-hydroxyallyloxy)biphenyl-2,2-diol (1), 5,5'-diallyl-2'-(allyloxy)biphenyl-2-ol (2), and 5,5'-diallyl-2'-(3-methylbut-2-enyloxy)biphenyl-2-ol (3), together with 12 known compounds, including four neolignans, magnolol (4), honokiol (5), (-)-monoterpenylmagnolol (6), and randainal (7), two norlignans, magnaldehyde D (8) and Randaiol (9), and six steroids, β-sitostenone (10), stigmasta-4,22-dien-3-one (11), β-sitosterol (12), stigmasterol (13), 3β-hydroxystigmast-5-en-7-one (14), and 3β-hydroxystigmasta-5,22-dien-7-one (15). The structure of new compounds (1-3) were determined through spectroscopic and MS analyses. Among the isolates, magnolol (4) and honokiol (5) exhibited potent inhibition against fMLP-induced superoxide production with IC50 values of 4.42±0.24 and 0.68±0.20μg/mL, respectively. In addition, magnolol (4) inhibited fMLP/CB-induced elastase release with an IC50 values of 1.45±0.20μg/mL.
    Citation [3]

    Chinese Traditional & Herbal Drugs, 2013 , 44 (3) :260-264.

    Chemical constituents in fractions with vasoactive activity from leaves of Magnolia officinalis[Reference: WebLink]
    To study the chemical constituents in the fractions with vasoactive activity from the dried leaves of Magnolia officinalis. Methods: The compounds were isolated from the chloroform and n-butanol fractions by various chromatographic techniques and identified by spectroscopic methods. Results: Sixteen compounds were obtained and identified as magnolol (1), magnaldehyde B (2), Randaiol (3), syringaresinol (4), 4, 4', 5-trihydroxy-1, 1'-di-2-propenylbiphenyl (5), lariciresinol (6), (7S, 8R) syringoylglycerol (7), coniferin (8), benzylic-β-D-allopyranoside (9), afzelin (10), isorhamnetin-3-O-β-D-glucoside (11), choerospondin (12), 5, 7-dihydroxy chromone-7-O-β-D-glucoside (13), erigeside C (14), tachioside (15), and uridine (16). Conclusion: Compounds 5-8 are isolated from this plant for the first time, and compounds 9-16 are isolated from this genus for the first time.