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Regaloside B
Regaloside B
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Regaloside B
Price: $238 / 20mg
CAS No.: 114420-67-6
Catalog No.: CFN91844
Molecular Formula: C20H26O11
Molecular Weight: 442.4 g/mol
Purity: >=98%
Type of Compound: Phenylpropanoids
Physical Desc.: Powder
Source: The rhizomes of Lilium brownii var. viridulum Baker
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $75.2 / In-stock
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Biological Activity
Description: Regaloside B can inhibit the expression of iNOS and COX-2. Regaloside B has anti-inflammatory activity.
In vitro:
Applied Biological Chemistry volume 60, pages527–533 (2017)
Phenylpropanoids from Lilium Asiatic hybrid flowers and their anti-inflammatory activities[Reference: WebLink]
Three phenylpropanoids were isolated from the flowers of Lilium Asiatic hybrids through repeated silica gel or octadecyl silica gel column chromatographies. The chemical structures were determined to be 1-O-trans-caffeoyl-β-D-glucopyranoside (1), regaloside A (2), and Regaloside B (3), based on spectroscopic data gathered from nuclear magnetic resonance (NMR) spectroscopy, electron ionization mass spectrometry (EI/MS), polarimetry, and infrared spectroscopy (IR) experiments. Compounds 1 and 2 showed significant DPPH radical scavenging activity of 60.1 and 58.0% at 160 ppm, respectively, compared with the 62.0% activity of the positive control, α-tocopherol. At a concentration of 50 μg/mL, compounds 1–3 inhibited the expression of iNOS to 4.1 ± 0.01, 70.3 ± 4.07, and 26.2 ± 0.63, respectively, and decreasing COX-2 expression to 67.8 ± 4.86, 131.6 ± 8.19, and 98.9 ± 4.99. Also, at the same concentration, compounds 1–3 decreased the ratio of p-p65/p-65 to 43.8 ± 1.67, 40.7 ± 1.30, and 43.2 ± 1.60, respectively, and the expression of VCAM-1 to 42.1 ± 2.31, 48.6 ± 2.65, and 33.8 ± 1.74, respectively.
Regaloside B Description
Source: The rhizomes of Lilium brownii var. viridulum Baker
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
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IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
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doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.2604 mL 11.302 mL 22.604 mL 45.208 mL 56.5099 mL
5 mM 0.4521 mL 2.2604 mL 4.5208 mL 9.0416 mL 11.302 mL
10 mM 0.226 mL 1.1302 mL 2.2604 mL 4.5208 mL 5.651 mL
50 mM 0.0452 mL 0.226 mL 0.4521 mL 0.9042 mL 1.1302 mL
100 mM 0.0226 mL 0.113 mL 0.226 mL 0.4521 mL 0.5651 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Phytochemistry, 1988, 27(2):451-454.
Regaloside A and B, acylated glycerol glucosides from Lilium regale.[Reference: WebLink]

METHODS AND RESULTS:
Novel acylated glycerol glucosides, regaloside A and Regaloside B, both bitter to the taste, have been isolated from the fresh bulbs of Lilium regale.
CONCLUSIONS:
Their structures have been shown by the spectral and chemical evidence to be (2S)-1-O-p-coumaroyl-3-O-β-d-glucopyranosylglycerol and (2S)-1-O-p-coumaroyl-2-O-β-d-glucopyranosyl-3-O-acetylglycerol, respectively.
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