|Source:||The roots of Salvia prionitis|
|Biological Activity or Inhibitors:|
|Solvent:||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.|
|Storage:||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
|After receiving:||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.|
|1 mg||5 mg||10 mg||20 mg||25 mg|
|1 mM||3.3738 mL||16.8691 mL||33.7382 mL||67.4764 mL||84.3455 mL|
|5 mM||0.6748 mL||3.3738 mL||6.7476 mL||13.4953 mL||16.8691 mL|
|10 mM||0.3374 mL||1.6869 mL||3.3738 mL||6.7476 mL||8.4345 mL|
|50 mM||0.0675 mL||0.3374 mL||0.6748 mL||1.3495 mL||1.6869 mL|
|100 mM||0.0337 mL||0.1687 mL||0.3374 mL||0.6748 mL||0.8435 mL|
Pharmaceutical Biology, 1999 , 37 (2) :148-151.
|Cytotoxic Activity of Diterpenoids Isolated from Salvia hypargeia[Reference: WebLink]|
|Ten diterpenoids [6a-hydroxysalvinolone ( 1 ), 6a-hydroxytaxodone ( 2 ), aethiopinone ( 3 ), microstegiol ( 4 ), ferruginol ( 5 ), Saprorthoquinone ( 6 ), 11,12-dioxoabieta-8,13-diene ( 7 ), taxodione ( 8 ), hypargenin A ( 9 ), hypargenin D ( 10 )] and three triterpenoids [lupeol 3-acetate, d-oleanol 3-acetate and -sitosterol] were isolated from the roots of Salvia hypargeia , a plant endemic to Turkey. The crude extract and compounds 1-2 , 5-10 were tested against a panel of human cancer cell lines [human breast cancer (BC 1), human lung cancer (LU 2), human colon cancer (COL 2), human epidermoidal carcinoma in mouth (KB), vinblastine-resistant KB-VI, hormone-dependent human prostate cancer (LNCaP)] as well as P388 and ASK cells in culture. The crude extract was active in all of the test systems, except KB. Isolates 1 and 8 were also found to mediate a generalized cytotoxic response.|