• ChemFaces is a professional high-purity natural products manufacturer.
  • Product Intended Use
  • 1. Reference standards
  • 2. Pharmacological research
  • 3. Inhibitors
  • Home
  • Natural Products
  • Bioactive
  • Screening Libraries
  • Hot Products
  • Plant Catalog
  • Customer Support
  • Product Use Citation
  • About Us
  • Contact Us
  • Natural Products
    Secologanin dimethyl acetal
    Information
    CAS No. 77988-07-9 Price
    Catalog No.CFN97683Purity>=98%
    Molecular Weight434.44Type of CompoundIridoids
    FormulaC19H30O11Physical DescriptionPowder
    Download Manual    COA    MSDSSimilar structuralComparison (Web)
    How to Order
    Orders via your E-mail:

    1. Product number / Name / CAS No.
    2. Delivery address
    3. Ordering/billing address
    4. Contact information
    Sent to Email: info@chemfaces.com
    Contact Us
    Order & Inquiry & Tech Support

    Tel: (0086)-27-84237683
    Fax: (0086)-27-84254680
    E-mail: manager@chemfaces.com
    Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
    Delivery time
    Delivery & Payment method

    1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

    2. We accept: Wire transfer & Credit card & Paypal & Western Union
    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    Our products had been exported to the following research institutions and universities, And still growing.
  • Centralised Purchases Unit (CPU)... (India)
  • Worcester Polytechnic Institute (USA)
  • Universidade de Franca (Brazil)
  • Kitasato University (Japan)
  • University of Minnesota (USA)
  • National Cancer Center Research ... (Japan)
  • Sant Gadge Baba Amravati Univers... (India)
  • Technical University of Denmark (Denmark)
  • Lodz University of Technology (Poland)
  • Universidad Industrial de Santan... (Colombia)
  • Tokyo Woman's Christian University (Japan)
  • More...
  • Package
    Featured Products
    8,8''-Bibaicalein

    Catalog No: CFN95007
    CAS No: 135309-02-3
    Price: $418/5mg
    Neochamaejasmine A

    Catalog No: CFN92151
    CAS No: 90411-13-5
    Price: $418/5mg
    Dictamnine

    Catalog No: CFN99783
    CAS No: 484-29-7
    Price: $178/20mg
    Neochamaejasmine B

    Catalog No: CFN92152
    CAS No: 90411-12-4
    Price: $418/5mg
    Isochlorogenic acid C

    Catalog No: CFN99120
    CAS No: 32451-88-0
    Price: $138/20mg
    Biological Activity
    Description: 1. Secologanin dimethyl acetal induces significant neurite outgrowth.
    Secologanin dimethyl acetal Description
    Source: The flower of Lonicera japonica Thunb
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
    Recent ChemFaces New Products and Compounds
    Columbianetin

    Catalog No: CFN90185
    CAS No: 3804-70-4
    Price: $268/20mg
    7-Hydroxyaristolochic acid A

    Catalog No: CFN90517
    CAS No: 79185-75-4
    Price: $220/5mg
    Licoricone

    Catalog No: CFN96504
    CAS No: 51847-92-8
    Price: $333/5mg
    7-Neohesperidosides

    Catalog No: CFN95018
    CAS No: 28383-41-7
    Price: $288/5mg
    Tectol

    Catalog No: CFN91054
    CAS No: 2449-39-6
    Price: $318/5mg
    Bruceine D

    Catalog No: CFN90771
    CAS No: 21499-66-1
    Price: $318/10mg
    Ganoderic acid DM

    Catalog No: CFN99815
    CAS No: 173075-45-1
    Price: $592/5mg
    Angelol G

    Catalog No: CFN92988
    CAS No: 83199-38-6
    Price: $198/10mg
    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.

    PMID: 29328914

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.

    PMID: 29149595

    Scientific Reports 2017 Dec 11;7(1):17332.
    doi: 10.1038/s41598-017-17427-6.

    PMID: 29230013

    Molecules. 2017 Oct 27;22(11). pii: E1829.
    doi: 10.3390/molecules22111829.

    PMID: 29077044

    J Cell Biochem. 2018 Feb;119(2):2231-2239.
    doi: 10.1002/jcb.26385.

    PMID: 28857247

    Phytomedicine. 2018 Feb 1;40:37-47.
    doi: 10.1016/j.phymed.2017.12.030.

    PMID: 29496173
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.3018 mL 11.5091 mL 23.0181 mL 46.0363 mL 57.5453 mL
    5 mM 0.4604 mL 2.3018 mL 4.6036 mL 9.2073 mL 11.5091 mL
    10 mM 0.2302 mL 1.1509 mL 2.3018 mL 4.6036 mL 5.7545 mL
    50 mM 0.046 mL 0.2302 mL 0.4604 mL 0.9207 mL 1.1509 mL
    100 mM 0.023 mL 0.1151 mL 0.2302 mL 0.4604 mL 0.5755 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Secologanin dimethyl acetal References Information
    Citation [1]

    J Nat Med. 2011 Jan;65(1):186-90.

    New physiological function of secoiridoids: neuritogenic activity in PC12h cells.[Pubmed: 20652643]
    Previously, we have reported that geniposide isolated from an extract of Gardenia fructus has neuritogenic activity in PC12h cells, a subclone of rat pheochromocytoma cells. Furthermore, we have indicated that several geniposide-related iridoid compounds also had similar potent neuritogenic activity. In this study, we have examined the effects of various secoiridoid compounds [K-1, sweroside; K-2, swertiamarin; K-3, gentiopicroside; K-4, 6'-O-β-D: -glucopyranosylsweroside; K-5, 6'-O-β-D: -glucopyranosylgentiopicroside; K-6, 6'-O-β-D: -glucopyranosylswertiamarin; K-7, 5'-O-β-D: -glucopyranosylamarogentin; K-8, 5'-O-β-D: -glucopyranosylamaroswertin; H-1, n-butyl vogeloside; H-2, n-butyl epivogeloside; H-3, (7S)-secologanin butyl methyl acetal; H-4, (7R)-secologanin butyl methyl acetal; H-5, Secologanin dimethyl acetal] isolated from various medicinal herbs. The secoiridoids H-1, H-2, H-3, H-4, and H-5 induced significant neurite outgrowth. Among these H-series compounds, H-2 was the most potent neuritogenic compound. Among the K-series compounds, K-1, K-2, K-3, and K-8 showed the most potent activity. These results suggest that secoiridoids have neuritogenic activity in PC12h cells and that these secoiridoid compounds are promising starting compounds for the development of neurotrophic factor-like and iridoid compounds.