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    Sennoside D
    Information
    CAS No. 37271-17-3 Price $218 / 20mg
    Catalog No.CFN99906Purity>=98%
    Molecular Weight848.76Type of CompoundAnthraquinones
    FormulaC42H40O19Physical DescriptionYellow powder
    Download Manual    COA    MSDSSimilar structuralComparison (Web)
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    Sennoside D Description
    Source: The leaves of Cassia angustifolia.
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.

    PMID: 29328914

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
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    PMID: 29230013

    Molecules. 2017 Oct 27;22(11). pii: E1829.
    doi: 10.3390/molecules22111829.

    PMID: 29077044

    J Cell Biochem. 2018 Feb;119(2):2231-2239.
    doi: 10.1002/jcb.26385.

    PMID: 28857247

    Phytomedicine. 2018 Feb 1;40:37-47.
    doi: 10.1016/j.phymed.2017.12.030.

    PMID: 29496173
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.1782 mL 5.8909 mL 11.7819 mL 23.5638 mL 29.4547 mL
    5 mM 0.2356 mL 1.1782 mL 2.3564 mL 4.7128 mL 5.8909 mL
    10 mM 0.1178 mL 0.5891 mL 1.1782 mL 2.3564 mL 2.9455 mL
    50 mM 0.0236 mL 0.1178 mL 0.2356 mL 0.4713 mL 0.5891 mL
    100 mM 0.0118 mL 0.0589 mL 0.1178 mL 0.2356 mL 0.2945 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Sennoside D References Information
    Citation [1]

    Chinese Journal of Experimental Traditional Medical Formulae,2012 ,18 (6) :10-12.

    Stability of Active Ingredients from Rheum officinale in Concentration and Drying Process.[Reference: WebLink]
    To study on stability of active ingredients from Rheum officinale in concentration and drying process.Method:Taking active ingredients from extraction fluid of R.officinale as studying target,samples were taken at different time points in concentration and drying progress,change trends of relative content was determined by HPLC.Result:The relative content of active ingredients were degraded greater degree after concentrated 1 h in process of heating at 70 ℃,its reduction is not obvious after concentrated 2 h by comparing with 1 h,but after concentrated for 3 h,the relative content reduced significantly;At 70 ℃ vacuum drying process,active ingredients were in large degree of degradation after drying 2 h,the change of content was small after drying 3 h by comparing with 2 h,general trend was relative stable,the content of active ingredients was less affected in drying process.Sennoside D decomposed easily in heating.Conclusion:During in process of concentration and drying at 70 ℃ vacuum for extraction fluid from R.officinale,concentration time should be controlled within 2 h,components were stable in drying time for 3 h.