Science | Nature | Cell | View More
Natural Products
Sequosempervirin B
Sequosempervirin B
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Sequosempervirin B
Price:
CAS No.: 864719-17-5
Catalog No.: CFN97905
Molecular Formula: C18H20O5
Molecular Weight: 316.4 g/mol
Purity: >=98%
Type of Compound: Lignans
Physical Desc.: Powder
Source: The heartwoods of Sequoia sempervirens
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • Periyar University (India)
  • Calcutta University (India)
  • Macau University of Science and... (China)
  • Chang Gung University (Taiwan)
  • University of Lodz (Poland)
  • University of Bonn (Germany)
  • CSIRO - Agriculture Flagship (Australia)
  • Max Rubner-Institut (MRI) (Germany)
  • Aarhus University (Denmark)
  • University of Indonesia (Indonesia)
  • Institute of Chinese Materia Me... (China)
  • More...
Package
Featured Products
Asperulosidic acid

Catalog No: CFN92108
CAS No: 25368-11-0
Price: $318/20mg
Ampelopsin

Catalog No: CFN98326
CAS No: 27200-12-0
Price: $30/20mg
Roemerine

Catalog No: CFN91019
CAS No: 548-08-3
Price: $318/5mg
Daidzein

Catalog No: CFN98774
CAS No: 486-66-8
Price: $30/20mg
Ginsenoside Rh1

Catalog No: CFN99970
CAS No: 63223-86-9
Price: $60/20mg
Trigonelline

Catalog No: CFN90225
CAS No: 535-83-1
Price: $40/20mg
Sinensetin

Catalog No: CFN99599
CAS No: 2306-27-6
Price: $100/20mg
Ganodermanondiol

Catalog No: CFN99085
CAS No: 107900-76-5
Price: $318/5mg
Ginsenoside Rh4

Catalog No: CFN92594
CAS No: 174721-08-5
Price: $368/10mg
Reynosin

Catalog No: CFN98344
CAS No: 28254-53-7
Price: $ /
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Sequosempervirin B is a natural product from Sequoia sempervirens.
In vitro:
Chem Biodivers. 2005 Apr;2(4):497-505.
Norlignans from Sequoia sempervirens.[Pubmed: 17191998 ]

METHODS AND RESULTS:
Six new norlignans, named Sequosempervirin B, sequosempervirin C,sequosempervirin D, sequosempervirin E, sequosempervirin F, sequosempervirin G (1-6), together with three known norlignans, agatharesinol (7), agatharesinol acetonide (8), and sugiresinol (9), were isolated from the branches and leaves of Sequoia sempervirens. Their structures were determined mainly by high-resolution mass spectroscopy (HR-MS), and various 1D- and 2D-NMR methods, as well as, in the case of 1, by means of X-ray diffraction.
CONCLUSIONS:
Compound 8 showed anticancer activity towards the A549 non-small-cell lung-cancer cell line (IC50 = 27.1 microM). The acetone extract of S. sempervirens was found to be antifungal towards Candida glabrata (IC50 = 15.98 microg/ml), and both the acetone and MeOH extracts inhibited the proteolytic activity of cathepsin B (IC50 = 4.58 and 5.49 microg/ml, resp.).
Sequosempervirin B Description
Source: The heartwoods of Sequoia sempervirens
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
2''-O-Galloylmyricitrin

Catalog No: CFN95046
CAS No: 56939-52-7
Price: $333/5mg
Violanone

Catalog No: CFN95385
CAS No: 52250-38-1
Price: $318/10mg
Erythro-Guaiacylglycerol-beta-coni...

Catalog No: CFN95416
CAS No: 74474-55-8
Price: $318/5mg
(-)-Epiafzelechin 3-O-gallate

Catalog No: CFN95081
CAS No: 108907-43-3
Price: $388/5mg
13(S)-Hydroxyoctadeca-9(Z),11(E)-d...

Catalog No: CFN95307
CAS No: 18104-45-5
Price: $318/10mg
Neoarctin B

Catalog No: CFN95243
CAS No: 155969-67-8
Price: $318/10mg
11-Oxomogroside IIA2

Catalog No: CFN95305
CAS No: 2170761-37-0
Price: $368/5mg
Gossypetin 3-sophoroside-8-glucosi...

Catalog No: CFN95528
CAS No: 77306-93-5
Price: $318/5mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.1606 mL 15.8028 mL 31.6056 mL 63.2111 mL 79.0139 mL
5 mM 0.6321 mL 3.1606 mL 6.3211 mL 12.6422 mL 15.8028 mL
10 mM 0.3161 mL 1.5803 mL 3.1606 mL 6.3211 mL 7.9014 mL
50 mM 0.0632 mL 0.3161 mL 0.6321 mL 1.2642 mL 1.5803 mL
100 mM 0.0316 mL 0.158 mL 0.3161 mL 0.6321 mL 0.7901 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Asperulosidic acid

Catalog No: CFN92108
CAS No: 25368-11-0
Price: $318/20mg
Ampelopsin

Catalog No: CFN98326
CAS No: 27200-12-0
Price: $30/20mg
Roemerine

Catalog No: CFN91019
CAS No: 548-08-3
Price: $318/5mg
Daidzein

Catalog No: CFN98774
CAS No: 486-66-8
Price: $30/20mg
Ginsenoside Rh1

Catalog No: CFN99970
CAS No: 63223-86-9
Price: $60/20mg
Trigonelline

Catalog No: CFN90225
CAS No: 535-83-1
Price: $40/20mg
Sinensetin

Catalog No: CFN99599
CAS No: 2306-27-6
Price: $100/20mg
Ganodermanondiol

Catalog No: CFN99085
CAS No: 107900-76-5
Price: $318/5mg
Ginsenoside Rh4

Catalog No: CFN92594
CAS No: 174721-08-5
Price: $368/10mg
Reynosin

Catalog No: CFN98344
CAS No: 28254-53-7
Price: $ /
Tags: buy Sequosempervirin B | Sequosempervirin B supplier | purchase Sequosempervirin B | Sequosempervirin B cost | Sequosempervirin B manufacturer | order Sequosempervirin B | Sequosempervirin B distributor