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    Sikokianin A
    Sikokianin A
    Information
    CAS No. 106293-99-6 Price $433 / 5mg
    Catalog No.CFN92155Purity>=98%
    Molecular Weight556.5Type of CompoundFlavonoids
    FormulaC31H24O10Physical DescriptionPowder
    Download     COA    MSDS    SDFSimilar structuralComparison (Web)
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    Sikokianin A Description
    Source: The roots of Stellera chamaejasme Linn.
    Biological Activity or Inhibitors: 1. Sikokianin A shows in vitro antiviral activity against HBsAg secretion.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.

    PMID: 29328914

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.

    PMID: 29149595

    Scientific Reports 2017 Dec 11;7(1):17332.
    doi: 10.1038/s41598-017-17427-6.

    PMID: 29230013

    Molecules. 2017 Oct 27;22(11). pii: E1829.
    doi: 10.3390/molecules22111829.

    PMID: 29077044

    J Cell Biochem. 2018 Feb;119(2):2231-2239.
    doi: 10.1002/jcb.26385.

    PMID: 28857247

    Phytomedicine. 2018 Feb 1;40:37-47.
    doi:10.1016/j.phymed.2017.12.030

    PMID: 29496173
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.7969 mL 8.9847 mL 17.9695 mL 35.9389 mL 44.9236 mL
    5 mM 0.3594 mL 1.7969 mL 3.5939 mL 7.1878 mL 8.9847 mL
    10 mM 0.1797 mL 0.8985 mL 1.7969 mL 3.5939 mL 4.4924 mL
    50 mM 0.0359 mL 0.1797 mL 0.3594 mL 0.7188 mL 0.8985 mL
    100 mM 0.018 mL 0.0898 mL 0.1797 mL 0.3594 mL 0.4492 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Sikokianin A References Information
    Citation [1]

    Chem Pharm Bull (Tokyo). 2005 Jul;53(7):776-9.

    Antimitotic and antifungal C-3/C-3''-biflavanones from Stellera chamaejasme.[Pubmed: 15997133]
    Two new C-3/C-3'' biflavanones, chamaejasmenin D (1) and isochamaejasmenin B (2), were isolated from the roots of Stellera chamaejasme, together with five known biflavanones, chamaejasmenin A (3), chamaejasmenin B (4), neochamaejasmin A (5), Sikokianin A (6), and chamaejasmenin C (7). Their structures were elucidated by spectroscopic methods, including 2D NMR techniques. Among these compounds, 1-3 demonstrated potent antimitotic and antifungal activity with minimum inhibitory concentration (MIC) values of 6.25, 6.25, and 3.12 microg/ml, respectively.
    Citation [2]

    Chem Biodivers. 2008 Jul;5(7):1419-24.

    Biflavanones, flavonoids, and coumarins from the roots of Stellera chamaejasme and their antiviral effect on hepatitis B virus.[Pubmed: 18649308 ]
    A new 3,3''-biflavanone, isoSikokianin A, was isolated from the roots of Stellera chamaejasme, together with eleven known compounds. Their structures and configurations were elucidated by spectroscopic methods including 2D-NMR techniques. Sikokianin A, chamaechromone, and quercetin showed in vitro antiviral activity against HBsAg secretion.