Science | Nature | Cell | View More
Natural Products
Soyasaponin Aa
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Soyasaponin Aa
Price:
CAS No.: 117230-33-8
Catalog No.: CFN90455
Molecular Formula: C64H100O31
Molecular Weight: 1365.46 g/mol
Purity: >=98%
Type of Compound: Triterpenoids
Physical Desc.: Powder
Source: The seeds of Glycine max
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • University of Lodz (Poland)
  • Calcutta University (India)
  • University of Mysore (India)
  • Shanghai Institute of Organic C... (China)
  • Utah State University (USA)
  • University of Vienna (Austria)
  • Helmholtz Zentrum München (Germany)
  • Weizmann Institute of Science (Israel)
  • Hamdard University (India)
  • Washington State University (USA)
  • University of Leipzig (Germany)
  • More...
Package
Featured Products
Tilianin

Catalog No: CFN92764
CAS No: 4291-60-5
Price: $218/20mg
Ginsenoside Rg6

Catalog No: CFN90565
CAS No: 147419-93-0
Price: $268/5mg
Oxoglaucine

Catalog No: CFN90508
CAS No: 5574-24-3
Price: $318/5mg
Tamarixetin

Catalog No: CFN97027
CAS No: 603-61-2
Price: $ /
Astragaloside I

Catalog No: CFN99172
CAS No: 84680-75-1
Price: $50/20mg
Isoscoparin

Catalog No: CFN90965
CAS No: 20013-23-4
Price: $138/10mg
Ophiopogonin D

Catalog No: CFN98156
CAS No: 41753-55-3
Price: $248/20mg
Notoginsenoside Fc

Catalog No: CFN93283
CAS No: 88122-52-5
Price: $198/20mg
trans-4-Hydroxycinnamic acid

Catalog No: CFN98794
CAS No: 501-98-4
Price: $30/20mg
Diosmetin

Catalog No: CFN90210
CAS No: 520-34-3
Price: $30/20mg
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Soyasaponin Aa and soyasaponin Ab dose-dependently markedly inhibit adipocyte differentiation and expression of various adipogenic marker genes, through the downregulation of the adipogenesis-related transcription factors PPARγ and C/EBPα in 3T3-L1 adipocytes.
Targets: PPAR
In vitro:
Phytother Res. 2015 Feb;29(2):281-7.
Soyasaponins Aa and Ab exert an anti-obesity effect in 3T3-L1 adipocytes through downregulation of PPARγ.[Pubmed: 25366162]
In this study, we investigated the effects and molecular mechanism of Soyasaponin Aa and soyasaponin Ab in regulating adipocyte differentiation and expression of adipogenic marker genes in 3T3-L1 adipocytes.
METHODS AND RESULTS:
Soyasaponin Aa and soyasaponin Ab dose-dependently inhibited the accumulation of lipids and the expression of adiponectin, adipocyte determination and differentiation factor 1/sterol regulatory element binding protein 1c, adipocyte fatty acid-binding protein 2, fatty acid synthase, and resistin in 3T3-L1 adipocytes. In addition, Soyasaponin Aa and soyasaponin Ab suppressed the transcriptional activity of peroxisome proliferator-activated receptor γ (PPARγ) in HEK 293T cells. Furthermore, we confirmed that the expression of PPARγ and of CCAAT-enhancer-binding protein α (C/EBPα) was suppressed at both the mRNA and protein levels in 3T3-L1 adipocytes by treatment with Soyasaponin Aa and soyasaponin Ab.
CONCLUSIONS:
Taken together, these findings indicate that Soyasaponin Aa and soyasaponin Ab markedly inhibit adipocyte differentiation and expression of various adipogenic marker genes through the downregulation of the adipogenesis-related transcription factors PPARγ and C/EBPα in 3T3-L1 adipocytes.
Soyasaponin Aa Description
Source: The seeds of Glycine max
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
2-(2,4-Dihydroxyphenyl)-5,6-methyl...

Catalog No: CFN95511
CAS No: 67121-26-0
Price: $318/5mg
Foliachinenoside C

Catalog No: CFN95361
CAS No: 1041180-87-3
Price: $368/5mg
Orcinol 1-O-beta-D-apiofuranosyl-(...

Catalog No: CFN95109
CAS No: 868557-54-4
Price: $338/5mg
Methylgomisin O

Catalog No: CFN95236
CAS No: N/A
Price: $318/5mg
Nortrachelogenin-5'-C-beta-glucosi...

Catalog No: CFN95251
CAS No: 858127-39-6
Price: $318/10mg
Arjungenin

Catalog No: CFN95039
CAS No: 58880-25-4
Price: $318/20mg
Carasiphenol C

Catalog No: CFN95045
CAS No: 868168-04-1
Price: $368/5mg
9-O-Acetyl-fargesol

Catalog No: CFN95031
CAS No: 449172-61-6
Price: $413/5mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 0.7324 mL 3.6618 mL 7.3235 mL 14.6471 mL 18.3088 mL
5 mM 0.1465 mL 0.7324 mL 1.4647 mL 2.9294 mL 3.6618 mL
10 mM 0.0732 mL 0.3662 mL 0.7324 mL 1.4647 mL 1.8309 mL
50 mM 0.0146 mL 0.0732 mL 0.1465 mL 0.2929 mL 0.3662 mL
100 mM 0.0073 mL 0.0366 mL 0.0732 mL 0.1465 mL 0.1831 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Tilianin

Catalog No: CFN92764
CAS No: 4291-60-5
Price: $218/20mg
Ginsenoside Rg6

Catalog No: CFN90565
CAS No: 147419-93-0
Price: $268/5mg
Oxoglaucine

Catalog No: CFN90508
CAS No: 5574-24-3
Price: $318/5mg
Tamarixetin

Catalog No: CFN97027
CAS No: 603-61-2
Price: $ /
Astragaloside I

Catalog No: CFN99172
CAS No: 84680-75-1
Price: $50/20mg
Isoscoparin

Catalog No: CFN90965
CAS No: 20013-23-4
Price: $138/10mg
Ophiopogonin D

Catalog No: CFN98156
CAS No: 41753-55-3
Price: $248/20mg
Notoginsenoside Fc

Catalog No: CFN93283
CAS No: 88122-52-5
Price: $198/20mg
trans-4-Hydroxycinnamic acid

Catalog No: CFN98794
CAS No: 501-98-4
Price: $30/20mg
Diosmetin

Catalog No: CFN90210
CAS No: 520-34-3
Price: $30/20mg
Tags: buy Soyasaponin Aa | Soyasaponin Aa supplier | purchase Soyasaponin Aa | Soyasaponin Aa cost | Soyasaponin Aa manufacturer | order Soyasaponin Aa | Soyasaponin Aa distributor