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Stigmasta-4,25-dien-3-one
Stigmasta-4,25-dien-3-one
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Stigmasta-4,25-dien-3-one
Price:
CAS No.: 848669-08-9
Catalog No.: CFN97407
Molecular Formula: C29H46O
Molecular Weight: 410.7 g/mol
Purity: >=98%
Type of Compound: Steroids
Physical Desc.: Powder
Source: The herbs of Porcelia macrocarpa
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Reference standards.
In vitro:
Marine Drugs, 2015, 13(7):4344-4356.
New α-Glucosidase Inhibitory Triterpenic Acid from Marine Macro Green Alga Codium dwarkense Boergs.[Reference: WebLink]
The marine ecosystem has been a key resource for secondary metabolites with promising biological roles.
METHODS AND RESULTS:
In the current study, bioassay-guided phytochemical investigations were carried out to assess the presence of enzyme inhibitory chemical constituents from the methanolic extract of marine green alga-Codium dwarkense. The bioactive fractions were further subjected to chromatographic separations, which resulted in the isolation of a new triterpenic acid; dwarkenoic acid (1) and the known sterols; androst-5-en-3β-ol (2), stigmasta-5,25-dien-3β,7α-diol (3), ergosta-5,25-dien-3β-ol (4), 7-hydroxyStigmasta-4,25-dien-3-one-7-O-β-d-fucopyranoside (5), 7-hydroxyStigmasta-4,25-dien-3-one (6), and stigmasta-5,25-dien-3β-ol (7). The structure elucidation of the new compound was carried out by combined mass spectrometry and 1D (1H and 13C) and 2D (HSQC, HMBC, COSY, and NOESY) NMR spectroscopic data. The sub-fractions and pure constituents were assayed for enzymatic inhibition of alpha-glucosidase.
CONCLUSIONS:
Compound 1 showed significant inhibition at all concentrations. Compounds 2, 3, 5, and 7 exhibited a dose-dependent response, whereas compounds 4-6 showed moderate inhibition. Utilizing such marine-derived biological resources could lead to drug discoveries related to anti-diabetics.
Stigmasta-4,25-dien-3-one Description
Source: The herbs of Porcelia macrocarpa
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.4349 mL 12.1743 mL 24.3487 mL 48.6973 mL 60.8717 mL
5 mM 0.487 mL 2.4349 mL 4.8697 mL 9.7395 mL 12.1743 mL
10 mM 0.2435 mL 1.2174 mL 2.4349 mL 4.8697 mL 6.0872 mL
50 mM 0.0487 mL 0.2435 mL 0.487 mL 0.9739 mL 1.2174 mL
100 mM 0.0243 mL 0.1217 mL 0.2435 mL 0.487 mL 0.6087 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Chicoric acid

Catalog No: CFN99725
CAS No: 6537-80-0
Price: $70/20mg
(Z)-Aldosecologanin (Centauroside)

Catalog No: CFN95079
CAS No: 82474-97-3
Price: $388/5mg
Naringenin

Catalog No: CFN98742
CAS No: 480-41-1
Price: $30/20mg
Chebulinic acid

Catalog No: CFN92296
CAS No: 18942-26-2
Price: $138/20mg
Poricoic acid A(F)

Catalog No: CFN92838
CAS No: 137551-38-3
Price: $218/20mg
Ganoderol B

Catalog No: CFN99064
CAS No: 104700-96-1
Price: $318/5mg
Chrysin

Catalog No: CFN98741
CAS No: 480-40-0
Price: $40/20mg
Afzelin

Catalog No: CFN98757
CAS No: 482-39-3
Price: $288/20mg
Luteolin

Catalog No: CFN98784
CAS No: 491-70-3
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Arctiin

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