Tanshinol B | CAS:189290-30-0 | Manufacturer ChemFaces

Tanshinol B

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Size /Price /Stock	10 mM * 1 mL in DMSO / Inquiry
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Tanshinol B Description

Source:	The roots of Salvia miltiorrhiza Bge.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Structure Identification:

Organic & Biomolecular Chemistry, 2018, 16.

Total synthesis of (±)-tanshinol B, tanshinone I, and (±)-tanshindiol B and C.[Reference: WebLink]

METHODS AND RESULTS:
A concise and efficient approach was established for the divergent total synthesis of (±)-tanshindiol B and C and tanshinone I from a ubiquitous ene intermediate in 1-2 steps. This critical intermediate was derived from (±)-Tanshinol B, which was synthesized in 50% overall yield over 3 steps using an ultrasound-promoted cycloaddition as a key step. Compared to a previously reported strategy, our approach is more step-economic, thus greatly improving the synthetic efficiency.
CONCLUSIONS:
The bioactivity evaluation indicates that the diol stereochemistry of the tanshidiols has an impact on the EZH2 inhibitory activity.

Product Name	Tanshinol B
Price:
CAS No.:	189290-30-0
Catalog No.:	CFN90370
Molecular Formula:	C₁₈H₁₆O₄
Molecular Weight:	296.32 g/mol
Purity:	>=98%
Type of Compound:	Diterpenoids
Physical Desc.:	Powder
Source:	The roots of Salvia miltiorrhiza Bge.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Neuroprotection Compound Library Antiangiogenic Compound Library Anti-Atherosclerotic Compound Library Anti-osteoporosis Compound Library Diterpenoids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	3.3747 mL	16.8737 mL	33.7473 mL	67.4946 mL	84.3683 mL
5 mM	0.6749 mL	3.3747 mL	6.7495 mL	13.4989 mL	16.8737 mL
10 mM	0.3375 mL	1.6874 mL	3.3747 mL	6.7495 mL	8.4368 mL
50 mM	0.0675 mL	0.3375 mL	0.6749 mL	1.3499 mL	1.6874 mL
100 mM	0.0337 mL	0.1687 mL	0.3375 mL	0.6749 mL	0.8437 mL

CFN92021	Przewaquinone C	96839-29-1	296.3	C₁₈H₁₆O₄
CFN92146	Tanshindiol B	97465-70-8	312.3	C₁₈H₁₆O₅
CFN92147	Tanshindiol C	97465-71-9	312.3	C₁₈H₁₆O₅
CFN92145	Tanshindiol A	97411-46-6	312.3	C₁₈H₁₆O₅
CFN99072	Tanshinlactone	105351-70-0	264.3	C₁₇H₁₂O₃
CFN97087	Neoprzewaquinone A	630057-39-5	556.6	C₃₆H₂₈O₆
CFN90348	3-Hydroxymethylenetanshinquinone	83145-47-5	294.30	C₁₈H₁₄O₄
CFN90333	1,2-Dihydrotanshinquinone	77769-21-2	278.3	C₁₈H₁₄O₃
CFN98953	Tanshinone I	568-73-0	276.3	C₁₈H₁₂O₃
CFN92645	Isosalviamine A	878475-29-7	287.3	C₁₉H₁₃NO₂