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Taxezopidine L
Taxezopidine L
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Taxezopidine L
Price:
CAS No.: 219749-76-5
Catalog No.: CFN96638
Molecular Formula: C39H46O15
Molecular Weight: 754.78 g/mol
Purity: >=98%
Type of Compound: Diterpenoids
Physical Desc.: Powder
Source: The seeds of the Japanese yew Taxus cuspidata Sieb. et Zucc.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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Biological Activity
Description: Taxezopidines K and taxezopidine L can markedly inhibit Ca2+-induced depolymerization of microtubules.
Targets: Calcium Channel
Taxezopidine L Description
Source: The seeds of the Japanese yew Taxus cuspidata Sieb. et Zucc.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.3249 mL 6.6244 mL 13.2489 mL 26.4978 mL 33.1222 mL
5 mM 0.265 mL 1.3249 mL 2.6498 mL 5.2996 mL 6.6244 mL
10 mM 0.1325 mL 0.6624 mL 1.3249 mL 2.6498 mL 3.3122 mL
50 mM 0.0265 mL 0.1325 mL 0.265 mL 0.53 mL 0.6624 mL
100 mM 0.0132 mL 0.0662 mL 0.1325 mL 0.265 mL 0.3312 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Tetrahedron, 1999,55(9):2553-2558.
Taxezopidines J, K, and L, new taxoids from Taxus cuspidata inhibiting Ca2+-induced depolymerization of microtubules.[Reference: WebLink]

METHODS AND RESULTS:
Three new taxoids, taxezopidine J (1), taxezopidine K (2), and Taxezopidine L (3), have been isolated from seeds of the Japanese yew Taxus cuspidata Sieb. et Zucc. and the structures were elucidated on the basis of spectroscopic data and chemical means.
CONCLUSIONS:
Taxezopidine K (2) and Taxezopidine L (3) markedly inhibited Ca2+-induced depolymerization of microtubules, while taxuspine D (4), a known taxoid from the yew, induced unusual shape change of mitotic spindles like taxol.
Isosilybin A

Catalog No: CFN91070
CAS No: 142796-21-2
Price: $218/5mg
(E)-6-O-(p-coumaroyl)scandoside me...

Catalog No: CFN95192
CAS No: 83946-90-1
Price: $218/10mg
Luteolin-4'-O-glucoside

Catalog No: CFN93776
CAS No: 6920-38-3
Price: $ / mg
Tilianin

Catalog No: CFN92764
CAS No: 4291-60-5
Price: $218/20mg
Neoglucobrassicin

Catalog No: CFN00503
CAS No: 5187-84-8
Price: $ / mg
Aurantiamide

Catalog No: CFN98984
CAS No: 58115-31-4
Price: $218/5mg
Isorhoifolin

Catalog No: CFN98927
CAS No: 552-57-8
Price: $318/10mg
Kaempferol-7-O-D-glucopyranoside

Catalog No: CFN90150
CAS No: 16290-07-6
Price: $268/5mg
Ganoderic acid C1

Catalog No: CFN92053
CAS No: 95311-97-0
Price: $218/5mg
Soybean phospholipid

Catalog No: CFN93800
CAS No: 8002-43-5
Price: $30/20mg
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