Science | Nature | Cell | View More
Natural Products
Taxiphyllin
Taxiphyllin
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Taxiphyllin
Price:
CAS No.: 21401-21-8
Catalog No.: CFN98070
Molecular Formula: C14H17NO7
Molecular Weight: 311.3 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The herbs of Pleioblastus amarus (Keng) Keng f.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • Universitas Airlangga (Indonesia)
  • Srinakharinwirot University (Thailand)
  • Nanjing University of Chinese M... (China)
  • University of Cincinnati (USA)
  • University of Virginia (USA)
  • China Medical University (Taiwan)
  • Lodz University of Technology (Poland)
  • Institute of Bioorganic Chemist... (Poland)
  • University of Madras (India)
  • Universiti Kebangsaan Malaysia (Malaysia)
  • Universidade Federal de Santa C... (Brazil)
  • More...
Package
Featured Products
Rutin

Catalog No: CFN99642
CAS No: 153-18-4
Price: $30/20mg
Stevioside

Catalog No: CFN99548
CAS No: 57817-89-7
Price: $40/20mg
Morusin

Catalog No: CFN97083
CAS No: 62596-29-6
Price: $128/20mg
Schisantherin D

Catalog No: CFN96704
CAS No: 64917-82-4
Price: $ / mg
Hypaconitine

Catalog No: CFN99200
CAS No: 6900-87-4
Price: $98/20mg
Mulberrin

Catalog No: CFN97085
CAS No: 62949-79-5
Price: $288/20mg
Pelargonidin-3-O-glucoside chloride

Catalog No: CFN92134
CAS No: 18466-51-8
Price: $490/10mg
Aucubin

Catalog No: CFN98530
CAS No: 479-98-1
Price: $60/20mg
Echinacoside

Catalog No: CFN98105
CAS No: 82854-37-3
Price: $30/20mg
Citreorosein

Catalog No: CFN98750
CAS No: 481-73-2
Price: $ /
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Taxiphyllin can inhibit tyrosinase activity in vitro significantly and is a potent tyrosinase inhibitor. Taxiphyllin displays mild antibacterial activity against Staphylococcus aureus.
Targets: Antifection | Tyrosinase
In vitro:
J Biol Chem. 1981 May 10;256(9):4253-8.
The in vitro biosynthesis of taxiphyllin and the channeling of intermediates in Triglochin maritima.[Pubmed: 7012151]
The in vitro biosynthesis of the cyanogenic glucoside Taxiphyllin has recently been demonstrated in Triglochin maritima (Hösel, W., and Nahrstedt, A. (1980) Arch. Biochem. Biophys. 203, 753-757).
METHODS AND RESULTS:
We have now studied in more detail the multistep conversion of tyrosine into p-hydroxymandelonitrile, the immediate precursor of Taxiphyllin, catalyzed by microsomes isolated from dark-grown seedlings. The biosynthetic pathway involves N-hydroxytyrosine, p-hydroxyphenylacetaldoxime, and p-hydroxyphenylacetonitrile. In marked contrast to an analogous pathway in Sorghum bicolor, p-hydroxyphenylacetonitrile is the best substrate for cyanide production (Vmax = 224 nmol/h/g, fresh wt) and the physiological substrate tyrosine is the poorest (Vmax = 18.8 nmol/h/g, fresh wt). The substrates exhibit alkaline pH optima between 7.5 and 9, and all except tyrosine show pronounced substrate inhibition. We have found that p-hydroxyphenylacetonitrile generated in situ from tyrosine is free to equilibrate by diffusion with exogenous material. On the other hand, neither N-hydroxytyrosine nor p-hydroxyphenylacetaldoxime will readily exchange with exogenous intermediates.
CONCLUSIONS:
We consider both N-hydroxytyrosine and p-hydroxyphenylacetaldoxime to be channeled in T. maritima, whereas in S. bicolor N-hydroxytyrosine and p-hydroxyphenylacetonitrile are channeled and the aldoxime is freely exchangeable.
J. Nat. Prod.,2006:69(9):1366-9.
Phytochemical constituents from Salsola tetrandra.[Pubmed: 16989538 ]

METHODS AND RESULTS:
The new norisoprenoid 3beta-hydroxy-5alpha,6alpha-epoxy-beta-ionone-2alpha-O-beta-d-glucopyranoside (1) and the long-chain hydroxy fatty acids 9,12,13-trihydroxyoctadeca-10(E),15(Z)-dienoic acid (2) and 9,12,13-trihydroxyoctadeca-10(E)-dienoic acid (3) were isolated from Salsola tetrandra aerial parts, together with 3,4,5-trimethoxyphenyl-beta-d-glucopyranoside (4), 9-hydroxylinaloyl glucoside (5), Taxiphyllin (6), trans-N-feruloyltyramine (7), and S-(-)-trans-N-feruloyloctopamine (8). Their structures were elucidated by extensive spectroscopic analysis and chemical methods.
CONCLUSIONS:
Compounds 6 and 8 displayed mild antibacterial activity against Staphylococcus aureus, whereas compound 6 showed the highest activity in the Artemia salina bioassay.
Taxiphyllin Description
Source: The herbs of Pleioblastus amarus (Keng) Keng f.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
(1E)-3-methoxy-8,12-epoxygermacra-...

Catalog No: CFN95219
CAS No: 1393342-06-7
Price: $413/5mg
Euphorbia factor L22

Catalog No: CFN95338
CAS No: 1613700-09-6
Price: $413/5mg
Octyl 3-(4-hydroxyphenyl)prop-2-en...

Catalog No: CFN95563
CAS No: N/A
Price: $318/5mg
Trachelogenin 4'-O-beta-gentiobios...

Catalog No: CFN95235
CAS No: 106647-13-6
Price: $218/10mg
Annphenone

Catalog No: CFN95426
CAS No: 61775-18-6
Price: $318/10mg
Picraquassioside B

Catalog No: CFN95378
CAS No: 169312-05-4
Price: $318/10mg
4,7-Didehydroneophysalin B

Catalog No: CFN95317
CAS No: 134461-76-0
Price: $338/5mg
5,7,2',4'-Tetrahydroxy-8,3'-di(gam...

Catalog No: CFN95084
CAS No: 141846-47-1
Price: $413/5mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.2123 mL 16.0617 mL 32.1234 mL 64.2467 mL 80.3084 mL
5 mM 0.6425 mL 3.2123 mL 6.4247 mL 12.8493 mL 16.0617 mL
10 mM 0.3212 mL 1.6062 mL 3.2123 mL 6.4247 mL 8.0308 mL
50 mM 0.0642 mL 0.3212 mL 0.6425 mL 1.2849 mL 1.6062 mL
100 mM 0.0321 mL 0.1606 mL 0.3212 mL 0.6425 mL 0.8031 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Kinase Assay:
Natural Product Research & Development, 2005, 17(6):733-725.
Taxiphyllin:A Cyanogenic Glucoside with Tyrosinase Inhibitory Activity from the Shoots of Pleioblastus amarus[Reference: WebLink]

METHODS AND RESULTS:
A cyanogenic glycoside,Taxiphyllin (1),was isolated from the shoots of Pleioblastus amarus (Keng) Keng f.for the first time.It's structure was elucidated on the basis of spectroscopic analysis (UV,IR,MS,1D and 2D NMR) and physiochemical properties.
CONCLUSIONS:
Taxiphyllin was found to inhibit tyrosinase activity in vitro significantly and considered to be a potent tyrosinase inhibitor.
Rutin

Catalog No: CFN99642
CAS No: 153-18-4
Price: $30/20mg
Stevioside

Catalog No: CFN99548
CAS No: 57817-89-7
Price: $40/20mg
Morusin

Catalog No: CFN97083
CAS No: 62596-29-6
Price: $128/20mg
Schisantherin D

Catalog No: CFN96704
CAS No: 64917-82-4
Price: $ / mg
Hypaconitine

Catalog No: CFN99200
CAS No: 6900-87-4
Price: $98/20mg
Mulberrin

Catalog No: CFN97085
CAS No: 62949-79-5
Price: $288/20mg
Pelargonidin-3-O-glucoside chloride

Catalog No: CFN92134
CAS No: 18466-51-8
Price: $490/10mg
Aucubin

Catalog No: CFN98530
CAS No: 479-98-1
Price: $60/20mg
Echinacoside

Catalog No: CFN98105
CAS No: 82854-37-3
Price: $30/20mg
Citreorosein

Catalog No: CFN98750
CAS No: 481-73-2
Price: $ /
Tags: buy Taxiphyllin | Taxiphyllin supplier | purchase Taxiphyllin | Taxiphyllin cost | Taxiphyllin manufacturer | order Taxiphyllin | Taxiphyllin distributor