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Triptinin B
Triptinin B
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Triptinin B
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CAS No.: 189389-05-7
Catalog No.: CFN96479
Molecular Formula: C20H26O3
Molecular Weight: 314.42 g/mol
Purity: >=98%
Type of Compound: Diterpenoids
Physical Desc.: Powder
Source: The roots of Tripterygium wilfordii Hook.f.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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Related Screening Libraries
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Biological Activity
Description: Triptinin A and triptinin B are leukotriene D4 antagonist constituents.
Triptinin B Description
Source: The roots of Tripterygium wilfordii Hook.f.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
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Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.1805 mL 15.9023 mL 31.8046 mL 63.6092 mL 79.5115 mL
5 mM 0.6361 mL 3.1805 mL 6.3609 mL 12.7218 mL 15.9023 mL
10 mM 0.318 mL 1.5902 mL 3.1805 mL 6.3609 mL 7.9511 mL
50 mM 0.0636 mL 0.318 mL 0.6361 mL 1.2722 mL 1.5902 mL
100 mM 0.0318 mL 0.159 mL 0.318 mL 0.6361 mL 0.7951 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Phytochemistry,1997,44 (8):1511-4.
Triptinins A and B, two leukotriene D4 antagonistic 19(4→3)-abeo-abietanes from Tripterygium wilfordii.[Reference: WebLink]

METHODS AND RESULTS:
Bioassay-directed separation of an ethanolic extract of the roots of Tripterygium wilfordii furnished two new 19(4→3)-abeo-abietanes, triptinin A and Triptinin B, along with two known diterpenes, triptoquinone A and 11-hydroxy-14-methoxy-19(4→3)-abeo-abieta-3, 8, 11, 13-tetraen-19-oic acid, as leukotriene D4 antagonist constituents.
CONCLUSIONS:
The structures of these diterpenes were elucidated by spectroscopic methods.
CFN99690Triptoquinonide163513-81-3326.4 C20H22O4
CFN91917Triptobenzene K198129-88-3342.39C20H22O5
CFN91913Neotriptophenolide81827-74-9342.43C21H26O4
CFN91912Triptohairic acid220209-71-2328.45C21H28O3
CFN99474Triptoquinone B142937-50-6330.4 C20H26O4
CFN96475Triptoquinone A142950-86-5328.40C20H24O4
CFN96479Triptinin B189389-05-7314.42C20H26O3
CFN96478Triptobenzene H146900-55-2344.45C21H28O4
CFN91646Triptonoterpene99694-87-8300.4C20H28O2
CFN99197Tripdiolide38647-10-8376.40C20H24O7
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