ChemFaces is a professional high-purity natural products manufacturer.
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1. Reference standards
2. Pharmacological research
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More articles cited ChemFaces products.
J Drug Target.2016 Feb 24:1-28.Phytomedicine. 2017 Jan 15;Evid Based Complement Alternat Med. 2016 May 24; Int. J. of Food Properties08 Feb 2017;Mol Med Rep.2015 Sep 21
RSC AdvancesIssue 86, 2017J. Soc. Cosmet. Sci. KoreaJune 2016Semyung UniversityJan. 2017;BMC Complement Altern Med.2014 Jul 14;14:242.FEBS Lett.2015 Jan 2;589(1):182-7.
Am J Chin Med.2016;44(8)Faculty of Chem. & Nat. Resource Eng.Jul. 2014Experimental Parasitology2015 March 24.Tea Res. Ins. Of ChinaJuly 13, 2017;
Our products had been exported to the following research institutions and universities, And still growing.
Deutsches Krebsforschungszentrum (Germany)Osmania University (India)Instytut Nawozów Sztucznych w P... (Poland)University of Hertfordshire (United Kingdom)
Universidade Federal de Pernambu... (Brazil)Weizmann Institute of Science (Israel)Seoul National University (Korea)Sri Sai Aditya Institute of Phar... (India)
Mahidol University (Thailand)Funda??o Universitária de Desen... (Brazil)Amity University (India)
Xanthohumol B Description
||The herbs of Humulus lupulus
|Biological Activity or Inhibitors:
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.PMID: 29328914
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.PMID: 29149595
Scientific Reports 2017 Dec 11;7(1):17332.doi: 10.1038/s41598-017-17427-6.PMID: 29230013
Molecules. 2017 Oct 27;22(11). pii: E1829.doi: 10.3390/molecules22111829.PMID: 29077044
J Cell Biochem. 2018 Feb;119(2):2231-2239.doi: 10.1002/jcb.26385. PMID: 28857247
Phytomedicine. 2018 Feb 1;40:37-47. doi:10.1016/j.phymed.2017.12.030PMID: 29496173
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Xanthohumol B References Information
Phytochemistry. 1997 Oct;46(4):683-7.
|Xanthohumols, diacylglycerol acyltransferase inhibitors, from Humulus lupulus.[Pubmed: 9366096]|
|A methanol extract of hops of Humulus lupulus (L.) showed inhibitory activity against rat liver diacylglycerol acyltransferase (DGAT). From DGAT inhibitory activity-guided fractionation, two chalcones were isolated. One was identified as xanthohumol and the other was found to be a new product designated Xanthohumol B. The structure of Xanthohumol B was shown to be 6-[3,4-dihydro-3,5-dihydroxy-7-methoxy-2,2-dimethyl-2H-benzo[b]pyrano ]- 3-(4-hydroxyphynyl)-2-propen-l-one by spectroscopic studies including various NMR measurements. Xanthohumol and Xanthohumol B inhibited DGAT activity with IC50 values of 50.3 and 194 microM in rat liver microsomes, respectively. They showed preferential inhibition of triacylglycerol formation in intact Raji cells, indicating that they inhibit DGAT activity preferentially in living cells.