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trans-Coutaric acid
trans-Coutaric acid
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name trans-Coutaric acid
Price:
CAS No.: 27174-07-8
Catalog No.: CFN70325
Molecular Formula: C13H12O8
Molecular Weight: 296.2 g/mol
Purity: >=98%
Type of Compound: Phenylpropanoids
Physical Desc.: Powder
Source: The pomace of Chardonnay grape.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Download: COA    MSDS
Similar structural: Comparison
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: trans-Coutaric acid has antioxidant activity.
In vitro:
Journal of Chemistry, 2016, 2016:1-8.
Antioxidant Composition of a Selection of Italian Red Wines and Their Corresponding Free-Radical Scavenging Ability.[Reference: WebLink]
This study correlates the antioxidant composition profiles and the overall antioxidant capacities of 36 Italian red wine samples.
METHODS AND RESULTS:
The samples were fully characterized by chromatographic and spectrophotometric techniques. The overall antioxidant capacity was determined by titrating a solution of the semistable free radical DPPH (1,1-diphenyl-2-picrylhydrazyl) with each wine sample followed by Electron Paramagnetic Resonance (EPR) spectroscopy and then measuring the resulting decrease in DPPH-signal. The antioxidant activities of the samples were expressed as (+)-catechin equivalents and related to their antioxidant composition profiles. Samples with a high polyphenol content showed a high DPPH scavenging ability as well. Seven well-defined groups, mainly constituted by wines coming from the same cultivar, were evidenced by PCA analysis. Alcohol content and pH did not influence the wine DPPH scavenging ability. The most important variables contributing to the winesa ™ antioxidant power are total flavonoid, total phenol, and proanthocyanidin indices together with fertaric acid, trans-caftaric acid, trans-Coutaric acid, and both quercetin glucoside and quercetin glucuronide.
CONCLUSIONS:
EPR is demonstrated to be faster than the other analytical methods (spectrophotometric and chromatographic analyses) to determine the wine overall antioxidant activity.
trans-Coutaric acid Description
Source: The pomace of Chardonnay grape.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

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Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.3761 mL 16.8805 mL 33.761 mL 67.5219 mL 84.4024 mL
5 mM 0.6752 mL 3.3761 mL 6.7522 mL 13.5044 mL 16.8805 mL
10 mM 0.3376 mL 1.688 mL 3.3761 mL 6.7522 mL 8.4402 mL
50 mM 0.0675 mL 0.3376 mL 0.6752 mL 1.3504 mL 1.688 mL
100 mM 0.0338 mL 0.1688 mL 0.3376 mL 0.6752 mL 0.844 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Food Chemistry, 1999, 65(1):1-8.
The polyphenol constituents of grape pomace.[Reference: WebLink]

METHODS AND RESULTS:
Chemical investigation of Chardonnay grape pomace has resulted in the isolation of 17 polyphenols which were identified by NMR spectroscopy as gallic acid, its 3- and 4-β-glucopyranosides, trans-caftaric acid, cis- and trans-Coutaric acid, 2-hydroxy-5-(2-hydroxyethyl)phenyl-β-glucopyranoside, catechin, epicatechin, procyanidin B1, quercetin 3-glucoside, quercetin 3-glucuronide, kaempferol 3-glucoside, kaempferol 3-galactoside, eucryphin, astilbin and engeletin.
CONCLUSIONS:
Gallic acid 3-β-glucopyranoside, gallic acid 4-β-glucopyranoside and 2-hydroxy-5-(2-hydroxyethyl)phenyl-β-glucopyranoside are reported here as natural grape constituents for the first time.
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