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    ChemFaces is a professional high-purity natural products manufacturer.

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    Natural Products
    Catalog No. Information
    CFN99183 (+)-Taxifolin

    1. (+)-Taxifolin is an inhibitor of aggregation of the 42-residue amyloid β-protein, it has preventive effects against Alzheimer's disease-like pathogenesis in vivo.
    2. (+)-Taxifolin is a weak inhibitor of cytochrome b5 reduction (IC50=9.8μM).
    CFN92796 (20R)-Ginsenoside Rh1

    1. 20S, 20R ginsenoside-Rh1 can inhibit the thrombin-induced conversion of fibrinogen to fibrin.
    CFN99979 (20R)-Protopanaxdiol

    1. Protopanaxdiol is effective in preventing and healing obesity, fatty liver and hypertriglyceridemia in mice fed with a high-fat diet.
    2. Protopanaxdiol has the effect of anti-tumor through increasing the activity of body immunity,improving the lymphocyte transformation,the activity of NK cells and the contents of IL-2 significantly.
    3. Protopanaxdiol inhibits tumor interstitial microvascular density and its proliferation activity, finally inhibits tumor growth.
    4. Protopanaxdiol can inhibit expression of vascular endothelial growth factor (VEGF) and basofibroblast growth factor(bFGF) protein,finally inhibits tumor growth of liver.
    5. (20R)-Protopanaxdiol has protective effect on myocardial ischemia, which may be related to improving free radicals metabolism and myocardial metabolism, decreasing plasma TXA 2 levels.
    CFN90564 (20S)-Protopanaxatriol

    1. (20S)-Protopanaxatriol shows strong and selective antimicrobial activity.
    2. (20S)-Protopanaxatriol is the inhibitor of farnesyl-protein transferase.
    3. (20S)-Protopanaxatriol exerts cardioprotective effects against myocardial ischemic injury, by enhancing the anti-free-radical actions of heart tissues.
    4. (20S)-Protopanaxatriol has anti-oxidant activity, can inhibit the elevation of malondialdehyde content, the reduction of superoxide dismutase activity, glutathione peroxidase and total antioxIdant capacity.
    CFN99764 (20S)-Protopanaxdiol

    20(S)-Protopanaxdiol may be a potential new P-gp inhibitor for cancer treatment, it may induce the apoptosis via the down-regulation of Bcl-2 protein and the up-regulation of γH2Ax protein expression; it may inhibit the proliferation of Siha cells via the up-regulating the expressions of p53, p21, and autophagy related gene Beclin 1and MAP1-LC3, and down-regulating the expression of cyclin-E.
    CFN99389 (2S,3S)-(-)-Glucodistylin

    1. Highest concentrations of (2R,3R)-(+)-glucodistylin, (2S,3S)-(-)-glucodistylin and 3-O-( -d-xylopyranosyl)taxifolin occur in European beeches can strongly infest with beech scale.
    CFN90143 (R)-(+)-Corypalmine

    1. (-)-Corypalmine has inhibition activity on spore germination of plant pathogenic and saprophytic fungi.
    CFN99735 (S)-10-Hydroxycamptothecin

    1. (S)-10-Hydroxycamptothecin (OPT), an analog of camptothecin (CPT), was found to inhibit the growth of the mouse hepatoma BW7756, when given at 1.0 mg/kg/day for 14 days; in spite of the narrow range of the effective dose of this drug against mouse hepatoma BW7756, the use of OPT in combination with other antitumor agents may be useful in primary hepatoma or liver metastases in view of its low toxicity towards host liver.
    2. (S)-10-Hydroxycamptothecin, as an inhibitor of the growth of P388 leukemia in mice, is as potent as the parent compound camptothecin (CPT).
    CFN96106 (Z)-Butylidenephthalide

    1. (Z)-Butylidenephthalide has antitumor effect, can effectively inhibit the tumor growth in the glioma.
    CFN90192 1,2,3,4,6-O-Pentagalloylglucose

    1. 1,2,3,4,6-Pentagalloylglucose(PGG) and gallic acid from Pistacia lentiscus have antimutagenic and antioxidant activities.
    2. PGG possesses potent anti-proliferative and anti-invasive effects, it also has inhibition of inducible nitric oxide synthase and cyclooxygenase-2 activity.
    3. PGG may serve as a model for the development of new types of anti-diabetic and anti-metabolic syndrome therapeutics.
    4. PGG has vasodilatory and anti-inflammatory effects, it dilates vascular smooth muscle and suppresses the vascular inflammatory process via endothelium-dependent nitric oxide (NO)/cGMP signaling.
    5. PGG can decrease the level of extracellular hepatitis B virus (HBV) (IC50, 1.0 microg/ml) in a dose-dependent manner, it also can reduce the HBsAg level by 25% at a concentration of 4 microg/ml; the gallate structure of PGG may play a critical role in the inhibition of anti-HBV activity, suggests that PGG could be a candidate for developing an anti-HBV agent.
    6. PGG has anti-parasitic activity, displays an EC50 value of 67 μM, at least 6.6-fold more effective than the standard drug benznidazole against trypomastigote forms of T. cruzi.