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    ChemFaces is a professional high-purity natural products manufacturer.

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    Natural Products
    Catalog No. Information
    CFN90367 12-O-tetradecanoylphorbol-13-acetate

    1. 12-O-tetradecanoylphorbol-13-acetate has skin tumor-promoting potential.
    2. 12-O-tetradecanoylphorbol-13-acetate induces endogenous FBXO10 mRNA and FBXO10 protein in Jurkat cells, a human T cell line.
    3. 12-O-tetradecanoylphorbol-13-acetate provokes cell motility through regulating the expression and function of S100A14 in a KLF4-dependent manner.
    CFN92232 13-Hydroxylupanine

    CFN98666 14-Deoxy-11,12-didehydroandrographolide

    1. 14-Deoxy-11,12-didehydroandrographolide (DDA) has hypotensive action, it causes negative chronotropic action and antagonised isoproterenol-induced positive chronotropic actions in a non-competitive and dose-dependent manner.
    2. DDA can retain the anti-inflammatory activities of andrographolide for asthma probably through the inhibition of NF-κB, it may be considered as a safer analogue of andrographolide for the potential treatment of asthma.
    3. DDA can effectively ameliorate astrocytic pro-inflammatory reactions and prevent PC12 cell death with different efficacies, it may be candidates for treatment of spinal-cord injury and neurodegeneration.
    4. DDA shows more potent cytotoxicity against human promonocytic leukemia (THP-1) cells than adherent cancer cell lines, it also shows antiproliferative action on both THP-1 and Jurkat cancer cell lines with low IC50 values.
    CFN92802 14-Deoxyandrographolide

    1. 14-Deoxyandrographolide desensitizes hepatocytes to TNF-alpha-mediated apoptosis through the release of TNFRSF1A.
    2. 14-Deoxyandrographolide has hepatoprotective activity, mediates activation of adenylate cyclase-cAMP signaling leading to up-regulation of cNOS, may provide a promising approach in the prevention of liver diseases during chronic alcoholism.
    CFN92122 1-Acetyl-beta-carboline

    1. Combination of 1-acetyl-beta-carboline with ampicillin exhibits synergistic antibacterial activity against MRSA.
    CFN92600 1beta-Hydroxyalantolactone

    1. 1beta-Hydroxyalantolactone has protective effect against AD-like skin inflammation, can as a potential therapeutic agent for AD.
    CFN99121 1-Caffeoylquinic acid

    1. 1-Caffeoylquinic acid has anti-influenza activity.
    2. 1-Caffeoylquinic acid is an important intermediate in lignin biosynthesis.
    3. 1-Caffeoylquinic acid is an antioxidant, also slows the release of glucose into the bloodstream after a meal.
    CFN92374 1-Dehydro-10-gingerdione

    1. 1-Dehydro-10-gingerdione has anti-inflammatory action, the molecular target is Myeloid differentiation protein.
    2. 1-Dehydro-10-gingerdione involves in the suppression of NF-κB-regulated gene expression in LPS-activated macrophages, has therapeutic potential in NF-κB-associated inflammation and autoimmune disorders.
    CFN92298 1-Dehydro-6-gingerdione

    1. 1-Dehydro-6-gingerdione is 5-HT1A receptor partial agonists.
    2. 1-Dehydro-6-gingerdione has antioxidant and anti-inflammatory activities.
    3. 1-Dehydro-6-gingerdione significantly suppresses the expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) proteins in a concentration-dependent fashion.
    CFN99933 1-Deoxynojirimycin

    1. 1-Deoxynojirimycin (DNJ), a potent glucosidase inhibitor, is beneficial for the suppression of abnormally high blood glucose levels and thereby prevention of diabetes mellitus, suggests that the newly developed DNJ-enriched powder can be used as a dietary supplement for preventing diabetes mellitus.
    2. 1-Deoxynojirimycin impairs oligosaccharide processing of alpha 1-proteinase inhibitor and inhibits its secretion in primary cultures of rat hepatocytes.
    3. 1-Deoxynojirimycin as a therapeutic agent by controlling the overgrowth and biofilm formation of S. mutans.
    4. 1-Deoxynojirimycin can block human immunodeficiency virus envelope glycoprotein- mediated membrane fusion at the CXCR4 binding step.