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    Natural Products
    Catalog No. Information
    CFN90340 20(R)-Ginsenoside Rh2

    1. 20(R)-Ginsenoside Rh2, a minor stereoisomer of ginsenoside Rh2, possesses matrix metalloproteinase inhibitory.
    2. 20(R)-Ginsenoside Rh2 has a significant inhibitory effect on the proliferation.
    3. 20(R)-Ginsenoside Rh2 has anti-inflammatory and antioxidative activities.
    4. 20(R)-Ginsenoside Rh2 shows selective osteoclastgenesis inhibitory activity without any cytotoxicity up to 100 microM.
    5. 20 (R)-ginsenoside Rh2 and 20(S)-ginsenoside Rh2 have anticancer effects and can increase inchoate apoptotic rate, reduce apoptotic rate significantly, enhance the activity of caspase-3 and induces apoptosis in human lung adenocarcinoma A549 cells.
    CFN99971 20(S)-Ginsenoside Rh2

    1. Ginsenoside Rh2 can suppress RANKL-induced osteoclast differentiation in vitro and in vivo through the regulation of c-Fos and NFATc1 expressions, not excluding the involvement of NF-κB and ERK, it is also suggested to be developed as a therapeutic drug for prevention and treatment of osteoporosis.
    2. Ginsenoside Rh2 has antitumor, antidiabetic, antiallergic, and anti-inflammatory effects.
    3. Ginsenoside Rh2 potently protects ischemia-reperfusion brain injury, also inhibits prostaglandin-E_2 synthesis in lipopolysaccharide-stimulated RAW264.7 cells, suggests it can improve ischemic brain injury.
    4. Ginsenoside Rh2 potently reverses memory impairment caused by scopolamine, it may improve learning deficits, also have the memory-enhancing effects of RGB.
    5. Ginsenoside Rh2 can suppress growth of uterine leiomyoma in vitro and in vivo and may regulate ERα/c-Src/p38 MAPK activity.
    6. Ginsenoside Rh2 can inhibit the tendency of apoptosis, and reverse the impaired β-cell growth potential by modulating Akt/Foxo1/PDX-1 signaling pathway and regulating cell cycle proteins, suggests its therapeutic potential in the treatment of diabetes.
    CFN92175 20-Deoxocarnosol

    1. 20-Deoxocarnosol , the main phenolic abietane present in aerial parts of the Chilean medicinal plant, has antioxidant activity of measuring the decay of the radical cation diphenyl-picrylhydrazyl (DPPH).
    2. 20-Deoxocarnosol exhibits non-specific antiprotozoal activity due to high cytotoxicity.
    CFN98873 20-Hydroxyecdysone

    1. 20-Hydroxyecdysone slowly reduces food consumption and then indirectly induces a state of starvation resulting in the elevation of the mRNA levels of InR , IRS , PI3K110 , and PDK in the Bombyx fat body during molting and pupation, and 20-hydroxyecdysone inhibits innate immunity in the fat body during Bombyx postembryonic development.
    2. 20-Hydroxyecdysone as ingredients in nutritional supplements for various sports, particularly bodybuilding.
    3. 20-Hydroxyecdysone induces autophagy and caspase activity, predominantly transduced by E93 in the remodeling fat body of Drosophila.
    4. 20-Hydroxyecdysone (via GPCR activation and calcium signaling) activates CaMKII phosphorylation and nuclear translocation, which regulate USP1 lysine acetylation to form an EcRB1-USP1 complex for 20E response gene transcription.
    5. 20-Hydroxyecdysone acts as both a positive and a negative regulator of EDG transcription, sequences in the promoter regions of two of the EDGs are similar to an ecdysone response element and may play a role in negative regulation.
    CFN90412 20R-Ginsenoside Rg2

    1. Ginsenoside Rg2 can protect H9c2 cells against H2O2- induced injury through its actions of anti-oxidant and anti-apoptosis.
    2. Ginsenoside Rg2 suppresses the hepatic glucose production via AMPK-induced phosphorylation of GSK3βand induction of SHP gene expression, it may have a therapeutic potential for type 2 diabetic patients.
    3. 20R-Ginsenoside Rg2 inhibits the cytokine interleukin 1 alpha (IL-1α)-induced reduction in gap junction-mediated intercellular communication (GJIC).
    CFN99496 24-Methylenecycloartan-3-ol

    1. 24-Methylenecycloartan-3-ol and methyl caffeate show weak activity against Staphylococcus aureus and Escherichia coli.
    CFN93572 25R-Inokosterone

    1. 25S-Inokosterone and 25R-inokosterone exhibit potent inhibition (80-95% at ) against TNF-expression levels in A23187 plus phorbol-myrisrate acetate-induced RBL-2H3 cells, they have excellent anti-atopy activity, thus they could be used to a large range of functional anti-atopy cosmetics.
    CFN93571 25S-Inokosterone

    1. 25S-Inokosterone and 25R-inokosterone exhibit potent inhibition (80-95% at ) against TNF-expression levels in A23187 plus phorbol-myrisrate acetate-induced RBL-2H3 cells, they have excellent anti-atopy activity, thus they could be used to a large range of functional anti-atopy cosmetics.
    CFN97032 2-Hydroxy-1,8-cineole

    1. 2-endo-Hydroxy-1,8-cineole shows antimicrobial and bactericidal activities against against test bacteria (Staphylococcus aureus, Escherichia coli, and Pseudomonas fluorescens) .
    CFN92111 2-Hydroxy-1-methoxyanthraquinone

    1. 2-Hydroxy-1-methoxy- anthraquinone can promote osteoblast proliferation, and can inhibit osteoclast TRAP activity and bone resorption, suggests that it has antiosteoporotic activity.