Screening Libraries
| Cat. | Size | Price | Stock | |
| T10069 | 1mg/well * 208 Compounds | Inquiry | In stock | Contact Us |
| T10069 | 100uL/well (10mM solution) * 208 Compounds | Inquiry | In stock |
| manager@chemfaces.com | |
| Tel | (0086)-27-8423-7683 |
| Shelf Life | (0086)-27-84254680 |
| Manufacturer | Wuhan ChemFaces Biochemical Co., Ltd. |
| Container | 96 Well Format Sample |
| Storage | Protected from air and light, refrigerate or freeze(2-8 °) |
| Shelf Life | 24 months (2-8 °) |
| Intended Use | For research use only. Not for human use. Not sell to patients |
| 1. The products in the ChemFaces screening libraries are all from plants. |
| 2. The biological activities or pharmacological activities of all the ChemFaces products are derived from the databases of all over the world the latest literatures, you can according to the product manuals on our website to access the relevant literatures, hope that our informations can give some inspirations and help to your research. |
| 3.The collections of unique natural products, which include antioxidants, anti-inflammatory, antibacterial, anticancer, and ect. Can be used for high throughput screening (HTS) and high content screening (HCS), is to help you carry out new drug screening, the emergence of new indications and other professional tools. |
| 4.Structurally diverse, medicinally active, and cell permeable, NMR and HPLC validated to ensure high purity. |
| 5. ChemFaces offers customized bioactive screening libraries , whereby you choose the specific compounds you want in the library, the quantities, plate map, concentration, and format (dry/solid or DMSO solution). |
| Catalog No. | Information |
| CFN99047 | Bakuchiol Bakuchiol possesses anti-tumor, cytotoxic, anti-bacterial , and anti-helmenthic properties, it shows DNA polymerase1 inhibiting activity. Bakuchiol has great potential for use in food additives and mouthwash for preventing and treating dental caries. |
| CFN99368 | Cedrelone Cedrelone exhibits antifeedant activity, it has insecticidal activity, it inhibits arval growth of P. saucia, and the molting of the milkweed bug, Oncopeltus fasciatus. Cedrelone and its derivatives exert antimicrobial activities, bromohydroxy cedrelone and Michael adduct show good antifungal activity. Cedrelone is also a very potent inducer of apoptosis, it can cause cell cycle arrest, it shows significant cytotoxicity against cancer cell lines, such as -60, SMMC-7721, A-549, MCF-7 and SW480. |
| CFN99382 | Pimaric acid Pimaric acid has potent anti-atherosclerotic activity with inhibitory action on matrix metalloproteinase-9 production and cell migration in TNF-α-induced human aortic smooth muscle cells. 4-epi-Pimaric acid shows antibacterial, anti-biofilm and anti-inflammatory potency , can be exploited for therapeutic application in oral microbial infections. |
| CFN99105 | Glycitin Glycitin has antibacterial, antiviral, anti-obese,anti-diabetic and estrogenic activities and may exert preventative effects on alcoholism, osteonecrosis,cardiovascular and cerebrovascular diseases and some types of cancer. It has a protective effect on skin aging by inhibiting of MMP-1 and increasing of collagen through ERK/JNK/P38 down-regulation, shows good inhibitory effect on α-glucosidase with IC50 of 0.5646 mg/mL. |
| CFN99106 | Glycitein Gycitein has antioxidant, weak estrogenic, anti-invasion, and anti-proliferation activities, it has potentiol to prevent Abeta associated neurodegenerative disorders, and atherosclerotic cardiovascular diseases. It is a potent activator of ERK1/2, decreases RWPE-1 cell proliferation, it induces ERK1/2 activation was dependent, in part, on tyrosine kinase activity associated with vascular endothelial growth factor receptor (VEGFR). |
| CFN99112 | Scutellarin Scutellarin has many pharmacological effects, such as antioxidant, antitumor, antiviral, neuroprotection and antiinflammatory activities. It down-regulates the STAT3/Girdin/Akt signaling in HCC cells, and inhibits RANKL-mediated MAPK and NF-κB signaling pathway in osteoclasts. |
| CFN99133 | Dendrobine Dendrobine is an antagonist of β-alanine, taurine and of presynaptic inhibition in the frog spinal cord. Dendrobine has antiviral, and antitumor activities; it can inhibit the growth of A549 cells through inducing apoptosis, which is partially dependent on mitochondrial-mediated pathway; dendrobine treatment decreased mitochondrial membrane potential (MMP), improved the expression of Bax and inhibited the expression of Bcl-2. |
| CFN99141 | Calycosin-7-O-beta-D-glucoside Calycosin-7-O-beta-D-glucoside, a melanin biosynthesis inhibitor, can protect BBB integrity in experimental cerebral ischemia–reperfusion injury via regulating NO/cav-1/MMPs pathway. It attenuates ischemia-reperfusion injuryin vivovia activation of the PI3K/Akt pathway, and has effects on cell apoptosis in cervical cancer HeLa cells and expression of Bcl-2/Bax. |
| CFN99142 | Genipin Genipin is an excellent natural cross-linker for proteins, collagen, gelatin, and chitosan cross-linking, can be used as a regulating agent for drug delivery, as the raw material for gardenia blue pigment preparation. It is a novel chemical activator of EBV lytic cycle and a cell permeable inhibitor of uncoupling protein 2 (UCP2). Genipin has antimicrobial,antiviral, antitumor, and anti-inflammatory effects, it is used for choleretic action for liver diseases control and could be used for the treatment of periodontal disease to prevent MMPs expression in periodontal lesion. It shows an antithrombotic effect in vivo due to the suppression of platelet aggregation. |
| CFN99147 | Ginsenoside Ro Ginsenoside Ro has antioxidative properties against UV-B-induced oxidative stress in human dermal fibroblasts, it possesses a potential skin anti-photoaging property against UV-B radiation in fibroblasts. It also exerts anti-apoptosis and anti-inflammation in IL-1β-induced rat chondrocytes, which might be related to NF-κB signal pathway, it might be a potential novel drug for the treatment of osteoarthritis. Ginsenoside Ro enhances in vivo hair re-growth based on their inhibitory activity against 5αR in the androgenetic alopecia model, it shows immunomodulatory effects by regulating the production and expression of Th1/Th2 cytokines in murine splenocytes. |
