Screening Libraries
| Cat. | Size | Price | Stock | |
| P20484 | 1mg/well * 10 Compounds | Inquiry | In stock | Contact Us |
| P20484 | 100uL/well (10mM solution) * 10 Compounds | Inquiry | In stock |
| manager@chemfaces.com | |
| Tel | (0086)-27-8423-7683 |
| Shelf Life | (0086)-27-84254680 |
| Manufacturer | Wuhan ChemFaces Biochemical Co., Ltd. |
| Container | 96 Well Format Sample |
| Storage | Protected from air and light, refrigerate or freeze(2-8 °) |
| Shelf Life | 24 months (2-8 °) |
| Intended Use | For research use only. Not for human use. Not sell to patients |
| 1. The products in the ChemFaces screening libraries are all from plants. |
| 2. The biological activities or pharmacological activities of all the ChemFaces products are derived from the databases of all over the world the latest literatures, you can according to the product manuals on our website to access the relevant literatures, hope that our informations can give some inspirations and help to your research. |
| 3.The collections of unique natural products, which include antioxidants, anti-inflammatory, antibacterial, anticancer, and ect. Can be used for high throughput screening (HTS) and high content screening (HCS), is to help you carry out new drug screening, the emergence of new indications and other professional tools. |
| 4.Structurally diverse, medicinally active, and cell permeable, NMR and HPLC validated to ensure high purity. |
| 5. ChemFaces offers customized bioactive screening libraries , whereby you choose the specific compounds you want in the library, the quantities, plate map, concentration, and format (dry/solid or DMSO solution). |
| Catalog No. | Information |
| CFN99916 | Beta-Sitosterol Beta-Sitosterol is a novel plant-derived angiogenic factor which may have potential pharmaceutical applications for the management of chronic wounds. It has potent anti-inflammatory, anti-proliferation, and pro- apoptosis activities, it also possesses antipyretic activity, similar to acetylsalicylic acid. |
| CFN99331 | Vanillic acid Vanillic acid is a flavoring agent which has hepatoprotective, free radical scavenging, antioxidant and anti-inflammatory properties. It exerts protective effects in isoproterenol induced cardiotoxic rats, has inhibitory effect on methylglyoxal-mediated glycation in apoptotic Neuro-2A cells via inhibition of glycation mechanisms including ROS, p38 and JNK, PKC and p47(phox). |
| CFN99107 | Isoimperatorin Isoimperatorin has analgesic, hepatoprotective, antimicrobial, anti-inflammatory, vascular relaxing and anticancer activities. It inhibited the expression of COX, TNF-α, PPAR-γ,ERK1/2, PI3K, and PKC. It showed significant inhibitory effects on acetylcholinesterase (AChE) with the IC50 of 74.6 uM, it also showed different inhibitory effects on all of the six CYP isoenzymes(human CYP1A2, 2B6, 2C9, 2C19, 2D6 and 3A4 enzymes). |
| CFN99100 | Succinic acid Succinic acid is a crystalline organic acid which occurs in living tissue as an intermediate in glucose metabolism. |
| CFN98758 | Imperatorin Imperatorin is an effective of NO synthesis inhibitor (IC50=9.2 μmol), which also is a BChE inhibitor (IC50=31.4 μmol); it is a weak agonist of TRPV1 with EC50 of 12.6±3.2 μM. Imperatorin is a potent myorelaxant agent and acts as a calcium antagonist on vascular smooth muscle. Imperatorin has anticonvulsant, anti-inflammatory, anti-oxidant, neuroprotection, and anti-cancer effects, it also has been used in herbal formulations for the treatment of hypertension and cardiovascular diseases. Imperatorin dampens neuronal excitability by inhibiting voltage-gated Na + channels (VGSC), and blocks the HSP27 and HSP72 gene expression. |
| CFN98713 | Daucosterol Daucosterol has neuroprotective activity, it has proliferation-enhancing activity for neural stem cells (NSCs), may be involved in IGF1-AKT pathway, and it as an efficient and inexpensive growth factor alternative that could be potentially developed as a medicine for ischemic stroke treatment, can significantly reduce neuronal loss.Daucosterol exhibits moderate antibacterial activity against Bacillus subtilis and Staphylococcus aureus; it has anti-cancer and apoptotic effects in human colon cancer cell line HCT-116, at different doses induces cell cycle arrest at sub-G1 phase of the cell cycle. |
| CFN98016 | Xanthotoxol Xanthotoxol shows strong pharmacological activities as anti-inflammatory, antioxidant, cytotoxic, dose-graded sedative, 5-HT antagonistic, and neuroprotective effects.Xanthotoxol also has calcium antagonistic effects, it blocks not only the voltage dependent calcium channel, but also the receptor operated calcium channel in the isolated guinea pig atria. |
| CFN97326 | Stigmasterol Stigmasterol is used as a precursor in the manufacture of synthetic progesterone, it is an antagonist of the bile acid nuclear receptor FXR, which has anti-inflammatory, thyroid inhibitory, cholesterol-lowering, antiperoxidative and hypoglycemic effects; it has indicated that stigmasterol may be useful in prevention of certain cancers, including ovarian, prostate, breast, and colon cancers. Stigmasterol inhibits the NF-kappaB pathway. |
| CFN90046 | D-Mannitol D-Mannitol, a specific hydroxyl free radical scavenger, can reduce the developmental toxicity of hydroxyurea in rabbits; it has thermal properties and could be as a Phase Change Material (PCM) for latent heat storage system; it is a potential diagnostic marker for aspergillosis. D-mannitol has neuroprotectant effect in reducing the sensory neurological disturbances seen in ciguatera poisoning, it does not act purely as an osmotic agent to reduce swelling of nerves, but involves a more complex action dependent on the Na(v) channel subtype, possibly to alter or reduce toxin association. |
| CFN98663 | 8-Hydroxy-5-O-beta-D-glucopyranosylpsoralen Standard reference |
